Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6231 | Asperuloside |
| Asperuloside exerts its anti-inflammatory effect in correlation with inhibition of a pro-inflammatory mediator through suppressing nuclear factor kappa-B (NF-κB) nuclear translocation and MAPK phosphorylation in a dose-dependent manner. Chronic administration of Asperuloside stimulates anti-obesity and anti-metabolic syndrome activity in HFD-fed rats across several organs, similar to Eucommia leaf extract (ELE) administration. | |
| BCN6232 | Daphylloside |
| Daphylloside, and asperuloside can be suggested as endoplasmic reticulum stress regulators. | |
| BCN6233 | Macrocarpal C |
| 1. Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation. | |
| BCN6239 | Neotuberostemonine |
| 1. Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. 2. Neotuberostemonine demonstrates antitussive properties in guinea pigs. | |
| BCN6240 | Dammarenediol II |
| 1. Dammarenediol II synthase is a key rate-limiting enzyme during the process of rice synthesizes dammarane-type ginsenosides. 2. Dammarenediol II can inhibit vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation and stress fiber formation and vascular endothelial-cadherin disruption, suggests that the natural drug dammarenediol II may have the ability to prevent diabetic microvascular complications, including diabetic retinopathy. 3. The medicinally important dammarenediol II can be ectopically produced in tobacco, and the production of dammarenediol-II in tobacco plants allows them to adopt a viral defense system. | |
| BCN6241 | Cinnamaldehyde |
| Cinnamaldehyde has vasodilator, anti-melanoma, hypoglycemic, hypolipidemic, and anticancer effects, it possesses anti-bacterial activity against both gram-positive and gram-negative bacteria. Cinnamaldehyde has toxicity and antifeedant activities against the grain storage insects, Tribolium castaneum (Herbst) and Sitophilus zeamais Motsch. Cinnamaldehyde inhibited the expression of VEGF and HIF-α.Cinnamic aldehyde, a COX-2 inhibitor, exhibits cardioprotective, antidepressant-like, anti-leukemia, anti-oxidative and anti-inflammatory properties. Its supplementation can improve glucose and lipid homeostasis in diabetic animals. | |
| BCN6244 | 2,24-Dihydroxyursolic acid |
| 1. 2,24-Dihydroxyursolic acid shows DPPH free radical scavenging and superoxide anion scavenging activity. | |
| BCN6246 | 6-O-Syringoylajugol |
| 1. 6-O-Syringoylajugol posseses antioxidant activity. | |
