SambutoxinCAS# 160047-56-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 160047-56-3 | SDF | Download SDF |
| PubChem ID | 54724817 | Appearance | Powder |
| Formula | C28H39NO4 | M.Wt | 453.6 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-[(2S,5R,6R)-6-[(E,4R,6S)-4,6-dimethyloct-2-en-2-yl]-5-methyloxan-2-yl]-4-hydroxy-5-(4-hydroxyphenyl)-1-methylpyridin-2-one | ||
| SMILES | CCC(C)CC(C)C=C(C)C1C(CCC(O1)C2=C(C(=CN(C2=O)C)C3=CC=C(C=C3)O)O)C | ||
| Standard InChIKey | FVYDVAOTXPELMH-SPRAOHHPSA-N | ||
| Standard InChI | InChI=1S/C28H39NO4/c1-7-17(2)14-18(3)15-20(5)27-19(4)8-13-24(33-27)25-26(31)23(16-29(6)28(25)32)21-9-11-22(30)12-10-21/h9-12,15-19,24,27,30-31H,7-8,13-14H2,1-6H3/b20-15+/t17-,18+,19+,24-,27+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers, it can cause toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, and, finally, death when rats were fed diets supplemented with 0.05 and 0.1% sambutoxin. 2. Sambutoxin inhibits rabbit platelet aggregation, which may be party due to the decrease of ATP release. 3. Sambutoxin has in vitro cytotoxicity against various human and murine tumor cells and values of sambutoxin ranged from 46.2 to 1,425.6 ng/ml. |
Sambutoxin Dilution Calculator
Sambutoxin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2046 mL | 11.0229 mL | 22.0459 mL | 44.0917 mL | 55.1146 mL |
| 5 mM | 0.4409 mL | 2.2046 mL | 4.4092 mL | 8.8183 mL | 11.0229 mL |
| 10 mM | 0.2205 mL | 1.1023 mL | 2.2046 mL | 4.4092 mL | 5.5115 mL |
| 50 mM | 0.0441 mL | 0.2205 mL | 0.4409 mL | 0.8818 mL | 1.1023 mL |
| 100 mM | 0.022 mL | 0.1102 mL | 0.2205 mL | 0.4409 mL | 0.5511 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Antibiotic AB 4063B
Catalog No.:BCN1827
CAS No.:160041-33-8
- Iniparib (BSI-201)
Catalog No.:BCC2208
CAS No.:160003-66-7
- Nelfinavir Mesylate
Catalog No.:BCC1794
CAS No.:159989-65-8
- Nelfinavir
Catalog No.:BCC4138
CAS No.:159989-64-7
- NIBR189
Catalog No.:BCC8056
CAS No.:1599432-08-2
- 3,5-Di-O-caffeoylquinic acid methyl ester
Catalog No.:BCN6491
CAS No.:159934-13-1
- Mc-Val-Cit-PABC-PNP
Catalog No.:BCC4028
CAS No.:159857-81-5
- 4'-O-Methylirenolone
Catalog No.:BCN7174
CAS No.:159853-36-8
- Sikokianin C
Catalog No.:BCN6827
CAS No.:159813-69-1
- Ulipristal
Catalog No.:BCC4944
CAS No.:159811-51-5
- Fmoc-Lys(Ac)-OH
Catalog No.:BCC3514
CAS No.:159766-56-0
- Ibutamoren Mesylate
Catalog No.:BCC1638
CAS No.:159752-10-0
- Huwentoxin XVI
Catalog No.:BCC8041
CAS No.:1600543-88-1
- Cryptofolione
Catalog No.:BCN7197
CAS No.:160098-78-2
- SCH 58261
Catalog No.:BCC7306
CAS No.:160098-96-4
- 2-Iminopiperidine hydrochloride
Catalog No.:BCC6862
CAS No.:16011-96-4
- L-BMAA hydrochloride
Catalog No.:BCC7400
CAS No.:16012-55-8
- 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
Catalog No.:BCC8779
CAS No.:160129-45-3
- BIM 23127
Catalog No.:BCC5822
CAS No.:160161-61-5
- SR 11302
Catalog No.:BCC3607
CAS No.:160162-42-5
- 14-Deoxy-11-hydroxyandrographolide
Catalog No.:BCN4702
CAS No.:160242-09-1
- SB 205384
Catalog No.:BCC7095
CAS No.:160296-13-9
- 8-Hydroxybergapten
Catalog No.:BCN2732
CAS No.:1603-47-0
- L-368,899 hydrochloride
Catalog No.:BCC7438
CAS No.:160312-62-9
Sambutoxin-producing isolates of fusarium species and occurrence of sambutoxin in rotten potato tubers.[Pubmed:16535155]
Appl Environ Microbiol. 1995 Oct;61(10):3750-1.
A total of 50 Fusarium isolates representing 13 species from various sources were surveyed to determine their potential to produce Sambutoxin. Sambutoxin production was restricted to Fusarium sambucinum and F. oxysporum, with the exception of one isolate of F. semitectum. Sambutoxin was produced by high percentages of F. sambucinum (80.0%) and F. oxysporum (84.6%) isolates at levels of 1.1 to 101.0 (mu)g/g. In addition, 9 (42.9%) of 21 rotten potato samples were contaminated with Sambutoxin at levels of 15.8 to 78.1 ng/g.
Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers.[Pubmed:7811078]
Appl Environ Microbiol. 1994 Dec;60(12):4380-6.
Ninety-nine isolates of Fusarium species were obtained from rotted potato tubers from various parts of Korea. Of these isolates, 80 were identified as Fusarium oxysporum, F. solani, or F. sambucinum. The isolates of these species were grown on autoclaved wheat grains and examined for toxicity in a rat-feeding test. A total of 8 of 57 F. oxysporum isolates, 3 of 14 F. solani isolates, and 5 of 9 F. sambucinum isolates caused the death of the rats. Of the 16 toxic isolates, 1 isolate of F. oxysporum produced a substantial amount of moniliformin, which could account for its toxicity. None of the other 15 isolates produced trichothecenes, moniliformin, fusarochromanone, fumonisin B1, or wortmannin. F. sambucinum PZF-4 produced an unknown toxin in wheat culture. This new toxin, given the trivial name Sambutoxin, caused toxic effects in rats, including body weight loss, feed refusal, hemorrhage in the stomach and intestines, and, finally, death when rats were fed diets supplemented with 0.05 and 0.1% Sambutoxin. The toxin was also toxic to chicken embryos, and the 50% lethal concentration was 29.6 micrograms per egg. Sambutoxin formed as white crystals that turned purple when combined with reagents such as sulfuric acid and p-anisaldehyde. It exhibited a green color immediately after treatment with potassium ferricyanide-ferric chloride. Its UV spectrum had absorption maxima at 213, 233, and 254 nm, and its infrared spectrum showed an amide group at 1,650 and 1,560 cm-1 and a hydroxy group at 3,185 cm-1. Mass spectrometry showed that the molecular weight of the toxin was 453 and the molecular formula was C28H39NO4.(ABSTRACT TRUNCATED AT 250 WORDS)
