Home >> Research Area >>Natural Products>>Coumarins>> 8-Hydroxybergapten

8-Hydroxybergapten

CAS# 1603-47-0

8-Hydroxybergapten

Catalog No. BCN2732----Order now to get a substantial discount!

Product Name & Size Price Stock
8-Hydroxybergapten: 5mg $150 In Stock
8-Hydroxybergapten: 10mg Please Inquire In Stock
8-Hydroxybergapten: 20mg Please Inquire Please Inquire
8-Hydroxybergapten: 50mg Please Inquire Please Inquire
8-Hydroxybergapten: 100mg Please Inquire Please Inquire
8-Hydroxybergapten: 200mg Please Inquire Please Inquire
8-Hydroxybergapten: 500mg Please Inquire Please Inquire
8-Hydroxybergapten: 1000mg Please Inquire Please Inquire

Quality Control of 8-Hydroxybergapten

Number of papers citing our products

Chemical structure

8-Hydroxybergapten

3D structure

Chemical Properties of 8-Hydroxybergapten

Cas No. 1603-47-0 SDF Download SDF
PubChem ID 3083726 Appearance Cryst.
Formula C12H8O5 M.Wt 232.19
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 9-hydroxy-4-methoxyfuro[3,2-g]chromen-7-one
SMILES COC1=C2C=COC2=C(C3=C1C=CC(=O)O3)O
Standard InChIKey MVJHUMZXIJPVHV-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 8-Hydroxybergapten

The roots of Angelica dahurica

Biological Activity of 8-Hydroxybergapten

Description8-Hydroxybergapten may have anti-wrinkle activity.
In vitro

Effect of Angelica. against Skin Photo-aging.[Reference: WebLink]

Journal of the Society of Cosmetic Scientists of Korea, 2005,31(3):227-35.

Skin aging is not a disease nor an abnormal phenomenon but a collection of degenerative changes with age, characterized by skin dryness, wrinkle formation, and loss of skin elasticity.
METHODS AND RESULTS:
The skin wrinkles are caused by either genetically predisposed factors or environmental factors such as UV irradiation or physical/chemical stimulus. The histological manifestations of wrinkles are changes in both amount and integrity of elastic and collagen fibers.
CONCLUSIONS:
Here we report the isolation and characterization of 3 active compounds, prangenidin, 8-Hydroxybergapten, and xanthotoxol from Angelica dahurica root. The anti-wrinkle activities of these compounds were also investigated.

8-Hydroxybergapten Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

8-Hydroxybergapten Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 8-Hydroxybergapten

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3068 mL 21.5341 mL 43.0682 mL 86.1364 mL 107.6704 mL
5 mM 0.8614 mL 4.3068 mL 8.6136 mL 17.2273 mL 21.5341 mL
10 mM 0.4307 mL 2.1534 mL 4.3068 mL 8.6136 mL 10.767 mL
50 mM 0.0861 mL 0.4307 mL 0.8614 mL 1.7227 mL 2.1534 mL
100 mM 0.0431 mL 0.2153 mL 0.4307 mL 0.8614 mL 1.0767 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 8-Hydroxybergapten

The biosynthesis of isopimpinellin.[Pubmed:890566]

Can J Biochem. 1977 Jul;55(7):686-92.

Bergapten and xanthotoxin, labelling in the methyl group wich carbon-14 or tritiated at three skeletal carbons, were administered to leaves of Heracleum lanatum and to cell cultures of Ruta graveolens. In all experiments xanthotoxin was the more efficient precursor of isopimpinellin, although bergapten was always incorporated to a measurable extent. Double-labelling experiments showed that both precursors, especially bergapten, underwent considerable demethylation (and presumably remethylation) before conversion to isopimpinellin. 5-Hydroxyxanthotoxin and 8-Hydroxybergapten were both O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-Hydroxy[Me-14C]bergapten was converted with a high degree of incorporation to isopimpinellin by Ruta cells in vivo, and it is suggested that the preference for the pathway via xanthotoxin may be due to more rapid hydroxylation of this substrate.

Description

8-hydroxybergapten is O-methylated by cell-free extracts of Ruta cells to isopimpinellin, in reactions mediated by discrete O-methyltransferases. 8-hydroxybergapten has excellent anti-wrinkle effect.

Keywords:

8-Hydroxybergapten,1603-47-0,Natural Products, buy 8-Hydroxybergapten , 8-Hydroxybergapten supplier , purchase 8-Hydroxybergapten , 8-Hydroxybergapten cost , 8-Hydroxybergapten manufacturer , order 8-Hydroxybergapten , high purity 8-Hydroxybergapten

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: