14-Deoxy-11-hydroxyandrographolideCAS# 160242-09-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 160242-09-1 | SDF | Download SDF |
PubChem ID | 91884987 | Appearance | Powder |
Formula | C20H30O5 | M.Wt | 350.45 |
Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 4-[(2R)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-2-hydroxyethyl]-2H-furan-5-one | ||
SMILES | CC12CCC(C(C1CCC(=C)C2C(CC3=CCOC3=O)O)(C)CO)O | ||
Standard InChIKey | BNLCOXWUZAOLDT-JLEOBMEESA-N | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. 14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells. |
14-Deoxy-11-hydroxyandrographolide Dilution Calculator
14-Deoxy-11-hydroxyandrographolide Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.8535 mL | 14.2674 mL | 28.5347 mL | 57.0695 mL | 71.3369 mL |
5 mM | 0.5707 mL | 2.8535 mL | 5.7069 mL | 11.4139 mL | 14.2674 mL |
10 mM | 0.2853 mL | 1.4267 mL | 2.8535 mL | 5.7069 mL | 7.1337 mL |
50 mM | 0.0571 mL | 0.2853 mL | 0.5707 mL | 1.1414 mL | 1.4267 mL |
100 mM | 0.0285 mL | 0.1427 mL | 0.2853 mL | 0.5707 mL | 0.7134 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- SR 11302
Catalog No.:BCC3607
CAS No.:160162-42-5
- BIM 23127
Catalog No.:BCC5822
CAS No.:160161-61-5
- 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one
Catalog No.:BCC8779
CAS No.:160129-45-3
- L-BMAA hydrochloride
Catalog No.:BCC7400
CAS No.:16012-55-8
- 2-Iminopiperidine hydrochloride
Catalog No.:BCC6862
CAS No.:16011-96-4
- SCH 58261
Catalog No.:BCC7306
CAS No.:160098-96-4
- Cryptofolione
Catalog No.:BCN7197
CAS No.:160098-78-2
- Huwentoxin XVI
Catalog No.:BCC8041
CAS No.:1600543-88-1
- Sambutoxin
Catalog No.:BCN1709
CAS No.:160047-56-3
- Antibiotic AB 4063B
Catalog No.:BCN1827
CAS No.:160041-33-8
- Iniparib (BSI-201)
Catalog No.:BCC2208
CAS No.:160003-66-7
- Nelfinavir Mesylate
Catalog No.:BCC1794
CAS No.:159989-65-8
- SB 205384
Catalog No.:BCC7095
CAS No.:160296-13-9
- 8-Hydroxybergapten
Catalog No.:BCN2732
CAS No.:1603-47-0
- L-368,899 hydrochloride
Catalog No.:BCC7438
CAS No.:160312-62-9
- Bisdehydroneotuberostemonine
Catalog No.:BCN7072
CAS No.:160333-27-7
- X-NeuNAc
Catalog No.:BCC2063
CAS No.:160369-85-7
- 3',5,5',7-Tetrahydroxyflavanone
Catalog No.:BCN1710
CAS No.:160436-10-2
- 30-Oxopseudotaraxasterol
Catalog No.:BCN7135
CAS No.:160481-71-0
- THZ1
Catalog No.:BCC4005
CAS No.:1604810-83-4
- THZ2
Catalog No.:BCC3986
CAS No.:1604810-84-5
- Antirhine
Catalog No.:BCN4003
CAS No.:16049-28-8
- Bisandrographolide A
Catalog No.:BCN4701
CAS No.:160498-00-0
- 12S-hydroxyandrographolide
Catalog No.:BCN4700
CAS No.:869593-50-0
Cell differentiation-inducing diterpenes from Andrographis paniculata Nees.[Pubmed:8069972]
Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1216-25.
The methanol extract of the aerial part of Andrographis paniculata Nees showed potent cell differentiation-inducing activity on mouse myeloid leukemia (M1) cells. From the ethyl acetate-soluble fraction of the methanol extract, six new diterpenoids of ent-labdane type, 14-epi-andrographolide (3), isoandrographolide (4), 14-deoxy-12-methoxyandrographolide (7), 12-epi-14-deoxy-12-methoxyandrographolide (8), 14-deoxy-12-hydroxyandrographolide (9) and 14-Deoxy-11-hydroxyandrographolide (10) as well as two new diterpene glucosides, 14-deoxy-11,12-didehydroandrographi-side (12) and 6'-acetylneoandrographolide (14), and four new diterpene dimers, bis-andrograpolides A (15), B (16), C (17) and D (18), were isolated along with six known compounds. The structures of the diterpenoids were determined by means of spectral methods. Some of these compounds showed potent cell differentiation-inducing activity towards M1 cells.