Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6165 | Protopine |
| Protopine acts as a potent inhibitor of thromboxane synthesis and PAF with hepatoprotective, antidepressant, antioxidant, antispasmodic and relaxant properties. Protopine is also a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. Protopine blocks phosphorylation of mitogen-activated protein kinases (MAP kinases) and also blocks activation of a nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB). | |
| BCN6166 | alpha-Yohimbine |
| 1. Alpha-Yohimbine is strong selective 2-adrenoceptor antagonist. 2. Alpha-Yohimbine possess aphrodisiac effect. 3. Alpha-Yohimbine is a 5-HT1A receptor agonist. | |
| BCN6167 | Dimethyl phthalate |
| Dimethyl phthalate is an organic compound, used as an insect repellent for mosquitoes and flies. | |
| BCN6168 | Pimpinellin |
| Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM. | |
| BCN6172 | 4-Epialyxialactone |
| 1. 4-Epialyxialactone exhibits significant antitumor and antibacterial activity. | |
| BCN6175 | Chrysophanol 8-O-glucoside |
| Chrysophanol-8-O-beta-D-glucopyranoside and chrysophanol have mild cytotoxicity and anti-diabetic properties and can play metabolic roles in the insulin-stimulated glucose transport pathway; it has potent inhibitory effect on collagen- and thrombin-induced platelet aggregation, it only inhibits platelet phosphatidylserine exposure.Chrysophanol-8-O-beta-D-glucopyranoside also exhibits significant anti-HBV activities with improved liver function, and enhanced HBeAg and HBsAg sero-conversion rates as well as HBV DNA clearance rates in HepG2 2.2.15 cells, DHBV models, or patients with chronic hepatitis B (CHB). | |
| BCN6176 | 15-Demethylplumieride |
| 1. 15-Demethylplumieride is a quality control index of Plumeriarubra L. | |
| BCN6178 | Macrocarpal A |
| 1. Macrocarpal A has cytotoxic activity. 2. Macrocarpal A has antibacterial activity. 3. Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum.. | |
