Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 4617 - 4624 of 9359 hot products
| Catalog No. | Product Name |
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| BCN2558 | Tetrahydrocoptisine |
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Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.
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| BCN2560 | Cirsilineol |
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1. Cirsilineol might be potentially useful for treating T-cell-mediated human inflammatory bowel diseases.
2. Cirsilineol has anti-proliferative activity against cancer cells by the induction of apoptosis via the mitochondrial pathway. |
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| BCN2561 | 4-Hydroxycoumarin |
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4-Hydroxycoumarin serves as an immediate precursor of 4-hydroxycoumarin (4HC) type anticoagulants (for example, warfarin).
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| BCN2562 | 7-Amino-4-methylcoumarin-3-acetic acid |
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1. 7-Amino-4-methylcoumarin is more suitable as a substrate for enteropeptidase than GD(4)K-NA.
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| BCN2563 | 4-Methylumbelliferone |
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4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM, which has antitumoral and antimetastatic effects. 4-Methylumbelliferone may inhibit the phosphorylation of HAS2 by PKC through the stimulation of O-GlcNAcylation; it also similarly ameliorates hypertriglyceridemia and hyperglycemia partly by modulating hepatic lipid metabolism and the antioxidant defense system along with increasing adiponectin levels.
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| BCN2564 | Amphotericin B |
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1. Amphotericin B is an antifungal agent.
2. Amphotericin B inhibits the A. actinomycetemcomitans-induced production of prostaglandin E2. 3. Amphotericin B can regulate inflammatory cytokines in host cells and regulate inflammatory responses in HGEC. 4. Amphotericin B inhibits the A. actinomycetemcomitans-induced phosphorylation of ERK and p38 MAP kinase. 5. The inhibition of the PKA signaling pathway can aid in reducing the degree of nephrotoxicity caused by Amphotericin B. 6. Treatment with Amphotericin B, particularly in combination with MCSF, increased the number of oligodendrocyte precursor cells and promoted remyelination within lesions. |
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| BCN2566 | Stachyose |
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Stachyose, as prebiotics, can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine.Stachyose inhibits Caco-2 cell proliferation and induces apoptosis in a dose-dependent manner. Stachyose with an RS3 carrier has better preventative effects on colitis than Stachyose alone in mice.
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| BCN2567 | D-Raffinose Pentahydrate |
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After treatment with CVGI, Raffinose family oligosaccharide was hydrolyzed effectively to yield galactose and sucrose. AA-PCD resistance in Raffinose-grown cells occurs with a decrease in both ROS production and cytochrome c release as compared to glucose-grown cells en route to AA-PCD.
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