Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 4625 - 4632 of 9359 hot products
| Catalog No. | Product Name |
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| BCN2568 | Mevastatin |
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Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway.
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| BCN2569 | Simvastatin |
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Simvastatin is an FDA-approved cholesterol-lowering medication, it possesses potent anti-inflammatory property and has potent benefits on endothelial and smooth muscle cell-mediated vasomotor responses. Simvastatin rescues Aβ-mediated cerebrovascular and cognitive deficits. Simvastatin reduces burn-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway, it induces p65 instability leads to MMP-9 down-regulation in leukemia cells, while it induces JNK1/c-Jun/ATF-2 activation maintains the MMP-2 expression underlying p65 down-regulation.
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| BCN2570 | Tenacissoside H |
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Tenacissoside H has antitumor activity on esophageal cancer through arresting cell cycle and regulating PI3K/Akt-NF-κB transduction cascade.
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| BCN2571 | L-Theanine |
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L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis. It is known to promote relaxation and improve concentration and learning ability and has neuroprotective effects. L-Theanine heals gastric ulcer and prevents CCl4-induced experimental hepatic cirrhosis in rats by blocking the main pro-inflammatory and pro-fibrogenic signals. L-Theanine can significantly alleviate the adverse oxidative effect.
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| BCN2572 | Kalopanaxsaponin H |
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1. Kalopanaxsaponin H has antidiabetic activity.
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| BCN2573 | Dihydroberberine |
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Dihydroberberine has anti-tumor activity. It also improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.
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| BCN2575 | Centaureidin |
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1. Centaureidin augments IFN-gamma promoter activity by approximately four-fold.
2. Centaureidin inhibits dendrite outgrowth from melanocytes by activating Rho, resulting in the inhibition of melanosome transfer from melanocytes to keratinocytes. 3. Centaureidin shows potential vasorelaxant activity. |
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| BCN2576 | Aloin B |
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Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation.
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