Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC4330 | Metoprolol Tartrate |
| Selective β1-adrenoceptor antagonist (Ki values are 47, 2960 and 10100 nM for β1, β2 and β3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo. | |
| BCC4333 | Oxymetazoline HCl |
| Partial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors. | |
| BCC4335 | Phenylephrine HCl |
| α1-adrenoceptor agonist; pKi values are 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively. | |
| BCC4338 | Salbutamol Sulfate |
| Non-selective β-adrenergic agonist, more potent at β2 than β1 receptors. | |
| BCC4340 | Timolol Maleate |
| β1-adrenergic blocker. | |
| BCC4343 | Betaxolol HCl |
| Selective β1-adrenoceptor antagonist. | |
| BCC4344 | Bisoprolol fumarate |
| A selective β1-adrenergic antagonist. Has a Kd of 2-3 nM at the β1 receptor and a β1/β2 selectivity of approximately 100-fold. | |
| BCC4347 | Dexmedetomidine HCl |
| Active isomer of medetomidine, a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). Displays greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. | |
