AlnustoneCAS# 33457-62-4 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 33457-62-4 | SDF | Download SDF |
| PubChem ID | 5317598 | Appearance | Powder |
| Formula | C19H18O | M.Wt | 262.35 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Synonyms | 1,7-Diphenyl 4,6-heptadiene 3-one | ||
| Solubility | Soluble in DMSO and methanol; insoluble in water | ||
| Chemical Name | (4E,6E)-1,7-diphenylhepta-4,6-dien-3-one | ||
| SMILES | C1=CC=C(C=C1)CCC(=O)C=CC=CC2=CC=CC=C2 | ||
| Standard InChIKey | OWMJDOUOHDOUFG-FNCQTZNRSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Alnustone has anti-inflammatory, antihepatotoxic and antiemetic activities, |
| Targets | Immunology & Inflammation related |
| In vivo | Three non-phenolic diarylheptanoids with anti-inflammatory activity from Curcuma xanthorrhiza.[Pubmed: 8255938]Planta Med. 1993 Oct;59(5):451-4.
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| Structure Identification | Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(16):2091-4.Qualitative and quantitative methods for Alpiniae Katsumadai semen[Pubmed: 21046736]The qualitative and quantitative methods for the quality evaluation of Alpiniae Katsumadai Semen were established. Alpinetin, pinocembrin, cardamonin and Alnustone in the sample were identified by TLC. |
Alnustone Dilution Calculator
Alnustone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.8117 mL | 19.0585 mL | 38.117 mL | 76.234 mL | 95.2925 mL |
| 5 mM | 0.7623 mL | 3.8117 mL | 7.6234 mL | 15.2468 mL | 19.0585 mL |
| 10 mM | 0.3812 mL | 1.9059 mL | 3.8117 mL | 7.6234 mL | 9.5293 mL |
| 50 mM | 0.0762 mL | 0.3812 mL | 0.7623 mL | 1.5247 mL | 1.9059 mL |
| 100 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.7623 mL | 0.9529 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Qualitative and quantitative methods for Alpiniae Katsumadai semen].[Pubmed:21046736]
Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(16):2091-4.
The qualitative and quantitative methods for the quality evaluation of Alpiniae Katsumadai Semen were established. Alpinetin, pinocembrin, cardamonin and Alnustone in the sample were identified by TLC. The contents of them were determined by HPLC. The separation was performed on a Ultimate XB-C18 column (4.6 mm x 250 mm, 5 microm) at 30 degrees C using a gradient elution consisting of mobile phase A (water) and mobile phase B (MeOH). The detection wavelength was 300 nm. The TLC method was suitable for the identification of alpinetin, pinocembrin, cardamonin and Alnustone. The linear ranges of the four reference compounds were 25.5-509 (r = 0.9999), 24.9-498 (r = 0.9999), 26.1-521 (r = 0.9999), 50.2-1003 ng (r = 0.9999), respectively. The average recoveries (n=9) of the four components were 97.95%, 97.36%, 97.50%, 98.02%, RSD < 1.9%. Nine samples were analyzed by the established methods. The results indicate that, the methods are simple, accurate, sensitive and reliable for quality evaluation of Alpiniae Katsumadai Semen.
Three non-phenolic diarylheptanoids with anti-inflammatory activity from Curcuma xanthorrhiza.[Pubmed:8255938]
Planta Med. 1993 Oct;59(5):451-4.
Bioassay-guided fractionation of a hexane extract of the rhizomes of Curcuma xanthorrhiza Roxb. (Zingiberaceae) led to the isolation of three non-phenolic diarylheptanoids, identified mainly by high-field 1H-NMR as trans-trans-1,7-diphenyl-1,3-heptadien-4-one (Alnustone), trans-1,7-diphenyl-1-hepten-5-ol, and trans,trans-1,7-diphenyl-1,3-heptadien-5-ol. The latter is reported for the first time as a plant constituent. Germacrone, curzerenone, and cinnamaldehyde were also isolated and identified. The three diarylheptanoids all exerted significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
