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3,3'-Bilawsone

CAS# 33440-64-1

3,3'-Bilawsone

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Product Name & Size Price Stock
3,3'-Bilawsone: 5mg Please Inquire In Stock
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Quality Control of 3,3'-Bilawsone

Number of papers citing our products

Chemical structure

3,3'-Bilawsone

3D structure

Chemical Properties of 3,3'-Bilawsone

Cas No. 33440-64-1 SDF Download SDF
PubChem ID 736158 Appearance Powder
Formula C20H10O6 M.Wt 346.29
Type of Compound Quinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-hydroxy-3-(1-hydroxy-3,4-dioxonaphthalen-2-yl)naphthalene-1,2-dione
SMILES C1=CC=C2C(=C1)C(=C(C(=O)C2=O)C3=C(C4=CC=CC=C4C(=O)C3=O)O)O
Standard InChIKey SXSJQXOTICWTFX-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H10O6/c21-15-9-5-1-3-7-11(9)17(23)19(25)13(15)14-16(22)10-6-2-4-8-12(10)18(24)20(14)26/h1-8,21-22H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 3,3'-Bilawsone

The herbs of Lomatia ferruginea

Biological Activity of 3,3'-Bilawsone

Description3,3'-Bilawsone is a natural product from Lomatia ferruginea.

Protocol of 3,3'-Bilawsone

Structure Identification
Phytochem Anal. 2010 Sep-Oct;21(5):444-50.

Simultaneous determination of three naphthoquinones in the leaves of Impatiens balsamina L. by reversed-phase high-performance liquid chromatography.[Pubmed: 20931623 ]

Naphthoquinones; lawsone (1), lawsone methyl ether (2) and methylene-3,3'-Bilawsone (3) are the main active compounds of Impatiens balsamina leaves. To develop and validate an HPLC method for simultaneous quantitative determination of 1-3 in I. balsamina leaf extracts.
METHODS AND RESULTS:
The method utilised a Supelco® C(18) column (5 μm, 4.6 × 150 mm) at 25°C with the mixture of 2% aqueous acetic acid : methanol (gradient elution as follows: 0-10 min, 25 : 75; 10-20 min, 32 : 68; 20-35 min, 55 : 45) as the mobile phase at a flow-rate of 1 mL/min, and UV detection at 280 nm. The parameters of linearity, repeatability, reproducibility, accuracy specificity and sensitivity of the method were evaluated.
CONCLUSIONS:
The recovery of the method was 96-101% and linearity (r(2) ≥ 0.9995) was obtained for all naphthoquinones. A high degree of specificity, as well as repeatability and reproducibility (RSD less than 5%), were also achieved.

3,3'-Bilawsone Dilution Calculator

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Preparing Stock Solutions of 3,3'-Bilawsone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8878 mL 14.4388 mL 28.8775 mL 57.7551 mL 72.1938 mL
5 mM 0.5776 mL 2.8878 mL 5.7755 mL 11.551 mL 14.4388 mL
10 mM 0.2888 mL 1.4439 mL 2.8878 mL 5.7755 mL 7.2194 mL
50 mM 0.0578 mL 0.2888 mL 0.5776 mL 1.1551 mL 1.4439 mL
100 mM 0.0289 mL 0.1444 mL 0.2888 mL 0.5776 mL 0.7219 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 3,3'-Bilawsone

Simultaneous determination of three naphthoquinones in the leaves of Impatiens balsamina L. by reversed-phase high-performance liquid chromatography.[Pubmed:20931623]

Phytochem Anal. 2010 Sep-Oct;21(5):444-50.

INTRODUCTION: Naphthoquinones; lawsone (1), lawsone methyl ether (2) and methylene-3,3'-bilawsone (3) are the main active compounds of Impatiens balsamina leaves. OBJECTIVE: To develop and validate an HPLC method for simultaneous quantitative determination of 1-3 in I. balsamina leaf extracts. METHODOLOGY: The method utilised a Supelco(R) C(18) column (5 microm, 4.6 x 150 mm) at 25 degrees C with the mixture of 2% aqueous acetic acid : methanol (gradient elution as follows: 0-10 min, 25 : 75; 10-20 min, 32 : 68; 20-35 min, 55 : 45) as the mobile phase at a flow-rate of 1 mL/min, and UV detection at 280 nm. The parameters of linearity, repeatability, reproducibility, accuracy specificity and sensitivity of the method were evaluated. RESULTS: The recovery of the method was 96-101% and linearity (r(2) >/= 0.9995) was obtained for all naphthoquinones. A high degree of specificity, as well as repeatability and reproducibility (RSD less than 5%), were also achieved.

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