Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5681 | Dihydrexidine hydrochloride |
| A potent, full efficacy dopamine D1 agonist which shows no agonist activity at peripheral D2 receptors or adrenoceptors at doses which cause maximal stimulation of D1 sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects in vivo. | |
| BCC5682 | RS 45041-190 hydrochloride |
| Highly selective I2 imidazoline receptor ligand. | |
| BCC5688 | ICI 215,001 hydrochloride |
| The active metabolite of ZD 7114. | |
| BCC5689 | p-Chlorophenylalanine |
| Binds irreversibly to tryptophan hydroxylase to cause depletion of serotonin in the brain. | |
| BCC5690 | Camstatin |
| An analog of PEP-19 with enhanced binding to and antagonism of calmodulin. | |
| BCC5691 | DCG IV |
| Presynaptic depressant; highly potent agonist for group II mGlu receptors. Also available as part of the Group II mGlu Receptor and Mixed mGlu Receptor. | |
| BCC5693 | RS 67333 hydrochloride |
| A potent and highly selective 5-HT4 partial agonist, with pKi values of 8.7 at 5-HT4 sites in guinea pig striatum and > 6 at various other receptors, including 5-HT1A, 1D, 2A, 2C, D1, D2 and M1-3. Active in vivo, with an intrinsic activity relative to 5-HT of 0.5. | |
| BCC5695 | L-745,870 trihydrochloride |
| A highly potent and selective D4 dopamine receptor antagonist; L-745,870 has Ki values of 0.51, 2300 and 960 nM for D4, D3 and D2 subtypes respectively and > 1000-fold selectivity over 5-HT2, D1 and D5 receptors. | |
