Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 6545 - 6552 of 9359 hot products
| Catalog No. | Product Name |
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| BCN4949 | Jujuboside A |
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Jujuboside A, a neuroprotective agent, can ameliorates behavioral disorders of the dementia mouse model induced by Aβ1-42. It possesses sedative , anticonvulsant , antianxiety, anti-proliferation, antioxidant, and anti-inflammatory effects, it can notably reduce the damage cause by ISO via promoting the phosphorylation of PI3K, Akt, and mTOR and inhibiting LC3 conversion, which may be a potential choice for the treatment of heart diseases. Jujuboside A can inhibit gamma aminobutyric acid type A receptor, and the hyperactivity of hippocampal CAl area induced by penicillin sodium.
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| BCN4950 | Jujuboside B |
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Jujuboside B has antitumor activity and the underlying mechanism via induction of apoptosis and autophagy. It reduces vascular tension endothelium-dependently by increasing Ca2+Influx and activating endothelial nitric oxide synthase, it has pharmacological effects on improving endothelial dysfunction and treating vascular diseases.
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| BCN4951 | Jujuboside D |
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1. Jujuboside D shows lipoxygenase-inhibiting activity.
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| BCN4952 | Prim-O-glucosylcimifugin |
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Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, has inhibition on NO production and DPPH free radical, it can inhibit the proliferation of smooth muscle cell stimulated by TNF-α and increase the proportion of G0/G1 phase.
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| BCN4953 | Echinacoside |
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Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.
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| BCN4954 | 5-O-Methylvisammioside |
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5-O-Methylvisammioside is a naturally occuring product isolated from Saposhnikovia Divaricata and has analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation effects.
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| BCN4955 | Isoalantolactone |
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Isoalantolactone, an apoptosis inducer, possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone induces apoptosis, may be mediated through caspase-dependent apoptotic pathways, S phase arrest, inhibition of phosphorylation of PI3K/Akt, and downregulation of Bcr/Abl.
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| BCN4956 | Jatrorrhizine chloride |
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Jatrorrhizine hydrochloride has lipid lowering effects, it can ameliorate hyperlipidemia via the suppression of lipogenesis and the enhancement of lipid oxidation in the liver. It
exhibits a potent inhibitory effect toward neuraminidase of the H7N9 (N9) avian influenza virus, it also can potentiate the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza. Jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate, can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity. |
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