Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5707 | L-733,060 hydrochloride |
| Potent NK1 antagonist (Ki values are 0.08, 0.2 and 93.13 nM for gerbil, human and rat receptors, respectively). Produces anxiolytic-like effects in the gerbil elevated plus-maze. Exhibits antitumor activity in vitro. Also decreases HER2 activity and tumor growth in mice bearing HER2+ or EGFR+ breast tumors. Orally bioavailable and brain penetrant. | |
| BCC5708 | Bombesin |
| Neuropeptide with many biological effects including hormone release, stimulation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. | |
| BCC5709 | CCK Octapeptide, non-sulfated |
| Non-sulfated form of the C-terminal octapeptide of CCK. Sulfated peptide also available. | |
| BCC5710 | CRF (human, rat) |
| Endogenous peptide agonist for the CRF receptor (Ki values are 11, 44 and 38 nM for hCRF1, rCRF2a and mCRF2b respectively). Stimulates the synthesis and release of ACTH from the anterior pituitary. | |
| BCC5711 | Pancreatic Polypeptide (human) |
| Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract. | |
| BCC5712 | CGRP (rat) |
| Endogenous neuropeptide; potent vasodilator which also exerts cardiovascular, pro-inflammatory and metabolic effects. | |
| BCC5713 | Endothelin 3 (human, rat) |
| Endogenous neuropeptide and potent vasoconstrictor. Displays selectivity for the putative ETC endothelin receptor. | |
| BCC5714 | Saralasin |
| Competitive non-selective angiotensin II antagonist. | |
