Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 6785 - 6792 of 9359 hot products
| Catalog No. | Product Name |
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| BCN5250 | Pinoresinol diacetate |
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1. Pinoresinol diacetate inhibits the enzyme α-glucosidase in vitro and may therefore act as a hypoglycemic agent.
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| BCN5251 | 10-Deacetylbaccatin III |
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10-Deacetylbacccatin III is an antineoplastic agent and an anti-cancer intermediate, it can selectively inhibit the growth of L. donovani intracellular amastigotes within J774 murine macrophages in vitro at nanomolar concentrations with an IC50 value of 70 nM.
The 10-Deacetylbaccatin III-treated promastigotes were slightly arrested in the G2/M phase whereas taxol-treated cells were blocked in the G2/M phase. |
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| BCN5252 | Kumatakenin |
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Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.
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| BCN5254 | Glucosyringic acid |
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1. Glucosyringic acid has immunosuppressive effect, it can inhibit the proliferation of murine B lymphocytes in vitro.
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| BCN5255 | 8-Deoxygartanin |
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1. 8-Deoxygartanin inhibits p65 activation with IC50 values of 11.3 microM.
2. 8-Deoxygartanin has cytotoxic effect on human melanoma cells, it is a potential candidate as anti-melanoma agents. 3. 8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor. 4. 8-Deoxygartanin exhibits significant inhibition of self-induced β-amyloid (Aβ) aggregation, it has multifunctional activities against Alzheimer's disease (AD) and could be promising compounds for the therapy of AD. 5. 8-Deoxygartanin has antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs. 6. 8-Deoxygartanin at 5 ug/ml can increase the cell cycle arrest in G(1) phase compared with untreated cells . |
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| BCN5256 | Gartanin |
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1. Gartanin possesses potent antioxidant, anti-inflammatory, antifungal and antineoplastic properties.
2. Gartanin induces protective autophagy mainly by JNK-Bcl-2 pathway. 3. Gartanin is an androgen receptor degradation enhancer. 4. Gartanin is a potential neuroprotective agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1αsignaling pathways. 5. Gartanin has anti-proliferation effect in T98G cells, which is most likely via cell cycle arrest modulated by autophagy, which is regulated by PI3K/Akt/mTOR signalling pathway, while its anti-migration effect is most likely via suppression of MMP-2/-9 activity which is involved in MAPK signalling pathway. |
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| BCN5257 | Quercetin 3,4'-dimethyl ether |
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1. Quercetin 3,4’-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM).
2. 5,7,3'-Trihydroxy-3,4'-dimethoxyflavone (Quercetin 3,4’-dimethyl ether ) has high cytotoxic against leukemia cells, it induces cell death is mediated by an intrinsic dependent apoptotic event involving mitochondria and MAPKs, and through a mechanism independent of the generation of reactive oxygen species, suggests that it could be useful in the development of novel anticancer agents. 3. Quercetin 3,4’-dimethyl ether shows anti-inflammatory activity. |
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| BCN5258 | Myricanol |
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1. Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells.
2. Myricanol can significantly decelerate tumor growth in vivo by inducing apoptosis. |
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