Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5887 | Rac1 Inhibitor F56, control peptide |
| Control peptide version of Rac1 Inhibitor W56; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction. | |
| BCC5888 | MNI-caged-NMDA |
| NMDA caged with the photosensitive 4-methoxy-7-nitroindolinyl group. | |
| BCC5889 | L803-mts |
| Selective peptide inhibitor of glycogen synthase kinase-3 (GSK-3). Produces antidepressive behavior in mice when administered in vivo. Shows no inhibition of PKC, PKB or cdc2 protein kinase. Exhibits insulin mimetic activity. Activates glycogen synthase activity 2.5-fold in HEK293 cells. Myristoylated version of L803. | |
| BCC5891 | GLP-2 (human) |
| Endogenous peptide identified as an intestinal epithelium-specific growth factor; stimulates cell proliferation and inhibits apoptosis. Diverse effects on gastrointestinal function including regulation of intestinal glucose transport, food intake, and gastric acid secretion. | |
| BCC5892 | GLP-2 (rat) |
| Endogenous peptide identified as an intestinal epithelium-specific growth factor; stimulates cell proliferation and inhibits apoptosis. Diverse effects on gastrointestinal function including regulation of intestinal glucose transport, food intake, and gastric acid secretion. | |
| BCC5894 | Motilin (human, porcine) |
| Endogenous motilin receptor ligand (Ki = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC50 = 1 nM) and increases pepsin release. | |
| BCC5896 | MNI-caged-D-aspartate |
| D-aspartate caged with the photosensitive 4-methoxy-7-nitroindolinyl group. Photolyzed by UV light with a quantum efficiency of 0.09 at pH 7.4. Agonist at NMDA receptors and EAAT substrate. | |
| BCC5897 | Tabimorelin hemifumarate |
| Potent, orally active ghrelin receptor (GHS-R1a) agonist (Ki = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats. | |
