Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5831 | [Leu5]-Enkephalin |
| Endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC50 = 11.4 nM). Short-acting in vivo. | |
| BCC5832 | Neuromedin C (porcine) |
| Mammalian bombesin-like neuropeptide; first isolated from pig spinal cord. Stimulates rat uterine smooth muscle contraction, and gastrin and somatostatin secretion in vitro. Increases blood pressure and pancreatic exocrine secretion in dogs in vivo. | |
| BCC5833 | Mastoparan X |
| Amphiphilic G protein activator peptide that binds to Gi and Go. Also binds with high affinity to calmodulin (Kd ~ 0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki = 4.4 mM). | |
| BCC5834 | Sarafotoxin S6a |
| Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo. | |
| BCC5835 | [Ala107]-MBP (104-118) |
| Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM). | |
| BCC5836 | [Ala113]-MBP (104-118) |
| Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM). | |
| BCC5838 | VIP (6-28) (human, rat, porcine, bovine) |
| VIP receptor antagonist. | |
| BCC5839 | Atrial natriuretic factor (1-28) (human, porcine) |
| Endogenous peptide produced by the heart; involved in blood pressure regulation. Produces natriuresis, diuresis and vasorelaxation in vivo. | |
