Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC5840 | Neuromedin N (rat, mouse, porcine, canine) |
| Endogenous neurotensin-like neuropeptide, originally isolated from porcine spinal cord. Binds to neurotensin receptors (IC50 = 16.7 nM for inhibition of [Trp11]-NT binding to rat brain receptors). Regulates guinea pig intestinal smooth muscle contraction and produces hypotension in rats. Also induces hypothermia following central administration in rats in vivo. | |
| BCC5841 | Neuromedin B (porcine) |
| Mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth. | |
| BCC5842 | Neurotensin |
| Brain and gastrointestinal peptide with many central and peripheral functions. Acts as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally, acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular system. | |
| BCC5843 | Atrial natriuretic factor (1-28) (rat) |
| Endogenous peptide produced by the heart; involved in blood pressure regulation. Produces natriuresis, diuresis and vasorelaxation in vivo. | |
| BCC5844 | [D-Phe12]-Bombesin |
| Bombesin receptor antagonist; inhibits bombesin-induced amylase release in guinea pig pancreas (IC50 = 4 mM). Centrally active in vivo. | |
| BCC5845 | Kinetensin (human) |
| Endogenous neurotensin-like peptide, originally isolated from pepsin-treated human plasma. Induces histamine release from rat peritoneal mast cells in vitro (ED50 ~ 10 mM). | |
| BCC5846 | Litorin |
| Amphibian bombesin-like peptide. Stimulates smooth muscle contraction, gastrin release, gastric acid and pancreatic secretion, and suppresses food intake in vivo. | |
| BCC5847 | Neuromedin U (rat) |
| Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo. | |
