Picrasin BCAS# 26121-56-2 |
Quality Control & MSDS
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| Cas No. | 26121-56-2 | SDF | Download SDF |
| PubChem ID | 5459138 | Appearance | Powder |
| Formula | C21H28O6 | M.Wt | 376.5 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1CC(C(=O)C2(C1CC3C4(C2C(=O)C(=C(C4CC(=O)O3)C)OC)C)C)O | ||
| Standard InChIKey | GESOKLRVLMVNMO-SOMOGOBTSA-N | ||
| Standard InChI | InChI=1S/C21H28O6/c1-9-6-13(22)19(25)21(4)11(9)7-14-20(3)12(8-15(23)27-14)10(2)17(26-5)16(24)18(20)21/h9,11-14,18,22H,6-8H2,1-5H3/t9?,11?,12-,13?,14?,18?,20+,21-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Picrasma quassioides (D. Don) Benn
| Description | 1. Picrasin B shows a significant clastogenic activity in cell cultures of Don lung cells of Chinese hamster. |
Picrasin B Dilution Calculator
Picrasin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.656 mL | 13.2802 mL | 26.5604 mL | 53.1208 mL | 66.4011 mL |
| 5 mM | 0.5312 mL | 2.656 mL | 5.3121 mL | 10.6242 mL | 13.2802 mL |
| 10 mM | 0.2656 mL | 1.328 mL | 2.656 mL | 5.3121 mL | 6.6401 mL |
| 50 mM | 0.0531 mL | 0.2656 mL | 0.5312 mL | 1.0624 mL | 1.328 mL |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2656 mL | 0.5312 mL | 0.664 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity.[Pubmed:19665539]
J Ethnopharmacol. 2009 Oct 29;126(1):114-8.
AIM OF THE STUDY: Our objective was to assess whether it could be contemplated to recommend Quassia amara young leaf tea for treatment against malaria, and if yes, set up a standard protocol for preparing the herbal tea. MATERIALS AND METHODS: The leaf tea was extracted with methylene chloride and the organic extract was fractionated with HPLC. Pure compounds were characterized and their in vitro cytotoxicity and antiplasmodial activity was determined. RESULTS AND DISCUSSION: We discovered that antimalarial Quassia amara young leaf tea contains several quassinoids: simalikalactone D (SkD, 1), Picrasin B (2), picrasin H (3), neoquassin (4), quassin (5), picrasin I (6) and picrasin J (7). These last two compounds are new. In addition, our experiments demonstrate that both biological activity and cytotoxicity of the remedy may be attributed solely to the presence of SkD. CONCLUSION: In conclusion, this preparation should not be recommended for treatment of malaria until a clinical study in humans is performed with SkD.
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