Denudatine

CAS# 26166-37-0

Denudatine

2D Structure

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Denudatine: 5mg $184 In Stock
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3D structure

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Denudatine

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Chemical Properties of Denudatine

Cas No. 26166-37-0 SDF Download SDF
PubChem ID 441729 Appearance White powder
Formula C22H33NO2 M.Wt 343.51
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in methan
SMILES CCN1CC2(CCCC34C2CC(C31)C56C4C(C(CC5)C(=C)C6O)O)C
Standard InChIKey OVXLNQAYPUEDSI-CNEDWAKUSA-N
Standard InChI InChI=1S/C22H33NO2/c1-4-23-11-20(3)7-5-8-22-15(20)10-14(18(22)23)21-9-6-13(12(2)19(21)25)16(24)17(21)22/h13-19,24-25H,2,4-11H2,1,3H3/t13-,14?,15-,16+,17-,18-,19-,20+,21+,22+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Denudatine

1 Delphinium sp. 2 Magnolia sp.

Biological Activity of Denudatine

Description1. Denudatine has effects on action potential of ventricular fibers and has inhibition on arrhythmogenic action of aconitine.

Denudatine Dilution Calculator

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Denudatine Molarity Calculator

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Preparing Stock Solutions of Denudatine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9111 mL 14.5556 mL 29.1112 mL 58.2225 mL 72.7781 mL
5 mM 0.5822 mL 2.9111 mL 5.8222 mL 11.6445 mL 14.5556 mL
10 mM 0.2911 mL 1.4556 mL 2.9111 mL 5.8222 mL 7.2778 mL
50 mM 0.0582 mL 0.2911 mL 0.5822 mL 1.1644 mL 1.4556 mL
100 mM 0.0291 mL 0.1456 mL 0.2911 mL 0.5822 mL 0.7278 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Denudatine

Antifungal diterpenoid alkaloids from Delphinium denudatum.[Pubmed:9170290]

J Nat Prod. 1997 May;60(5):472-4.

The roots of Delphinium denudatum have yielded a new diterpenoid alkaloid, 8-acetylheterophyllisine (1), in addition to the known alkaloids vilmorrianone (2), panicutine (3), Denudatine (4), isotalatizidine (5), and condelphine (6), as well as 3-hydroxy-2-methyl-4H-pyran-4-one (7). Compounds 1, 3, and 7 have not been isolated from this plant previously. The structures of compounds 1, 3, and 7 were determined through spectral and X-ray diffraction analyses. Compounds 1-3 have shown antifungal activity against a number of human pathogenic fungi.

Description

Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium. Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine.

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