Foliamenthoic acidCAS# 26187-80-4 |
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3D structure
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| Cas No. | 26187-80-4 | SDF | Download SDF |
| PubChem ID | 12681385 | Appearance | Oil |
| Formula | C10H16O3 | M.Wt | 184.2 |
| Type of Compound | Monoterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2E,6E)-8-hydroxy-2,6-dimethylocta-2,6-dienoic acid | ||
| SMILES | CC(=CCO)CCC=C(C)C(=O)O | ||
| Standard InChIKey | SMFMBDDFGPDMMD-RFSWUZDDSA-N | ||
| Standard InChI | InChI=1S/C10H16O3/c1-8(6-7-11)4-3-5-9(2)10(12)13/h5-6,11H,3-4,7H2,1-2H3,(H,12,13)/b8-6+,9-5+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Foliamenthoic acid shows α-glucosidase inhibition. |
Foliamenthoic acid Dilution Calculator
Foliamenthoic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.4289 mL | 27.1444 mL | 54.2888 mL | 108.5776 mL | 135.722 mL |
| 5 mM | 1.0858 mL | 5.4289 mL | 10.8578 mL | 21.7155 mL | 27.1444 mL |
| 10 mM | 0.5429 mL | 2.7144 mL | 5.4289 mL | 10.8578 mL | 13.5722 mL |
| 50 mM | 0.1086 mL | 0.5429 mL | 1.0858 mL | 2.1716 mL | 2.7144 mL |
| 100 mM | 0.0543 mL | 0.2714 mL | 0.5429 mL | 1.0858 mL | 1.3572 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Phytochemical and Pharmacological Investigations on Nymphoides indica Leaf Extracts.[Pubmed:27282639]
Phytother Res. 2016 Oct;30(10):1624-1633.
Nymphoides indica (L.) Kuntze (Menyanthaceae) is traditionally used in the Indian subcontinent. However, scientific data reporting its constituents are poor. This study aimed at evaluating its phytochemical constituents and various biological activities. Phytochemical investigations of the extracts and fractions resulted in the isolation of 5 lipophilic compounds, i.e. azelaic (nonanedioic) acid (1) and 4-methyl-heptanedioic acid (3), hexadecanoic (2) and stearic acid (5) and the fatty alcohol hexadecanol (4); 3 seco-iridoids, i.e. 7-epiexaltoside (6), 6'',7''-dihydro-7-epiexaltoside (7) and menthiafolin (8); 3 flavonoids, i.e. 3,7-di-O-methylquercetin-4'-O-beta-glucoside (9), 3-O-methylquercetin-7-O-beta-glucoside (10) and 3,7-di-O-methylquercetin (11); scopoletin (12) and ferulic acid (13); and the monoterpenoids Foliamenthoic acid (14) and 6,7-dihydroFoliamenthoic acid methyl ester (15). Compounds 1-5 showed moderate antimicrobial activities, whereas compound 9 presented mild antiprotozoal activities against Trypanosoma brucei (IC50 8 muM), Leishmania infantum (IC50 32 muM) and Trypanosoma cruzi (IC50 30 muM). Antiglycation activity was shown by compounds 7 (IC50 0.36 mM), 10 (IC50 0.42 mM) and 15 (IC50 0.61 mM). Finally alpha-glucosidase inhibition was shown by compounds 7, 9, 11 and 13-15. It could be concluded that N. indica leaf extracts possess mild to moderate antimicrobial, antiprotozoal, antioxidant and antidiabetic activities. Copyright (c) 2016 John Wiley & Sons, Ltd.
