1,2-Methylenedioxy-3,10,11-trimethoxynoraporphineCAS# 14050-90-9 |
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| Cas No. | 14050-90-9 | SDF | Download SDF |
| PubChem ID | 91884709 | Appearance | Powder |
| Formula | C20H21NO5 | M.Wt | 355.4 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | COC1=C(C2=C(CC3C4=C2C5=C(C(=C4CCN3)OC)OCO5)C=C1)OC | ||
| Standard InChIKey | CHTZCWLHHIYAJY-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Cassytha filiformis
| Description | 1. 1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations. |
1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine Dilution Calculator
1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8137 mL | 14.0687 mL | 28.1373 mL | 56.2746 mL | 70.3433 mL |
| 5 mM | 0.5627 mL | 2.8137 mL | 5.6275 mL | 11.2549 mL | 14.0687 mL |
| 10 mM | 0.2814 mL | 1.4069 mL | 2.8137 mL | 5.6275 mL | 7.0343 mL |
| 50 mM | 0.0563 mL | 0.2814 mL | 0.5627 mL | 1.1255 mL | 1.4069 mL |
| 100 mM | 0.0281 mL | 0.1407 mL | 0.2814 mL | 0.5627 mL | 0.7034 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Vasorelaxing alkaloids and flavonoids from Cassytha filiformis.[Pubmed:18217715]
J Nat Prod. 2008 Feb;71(2):289-91.
Two new aporphine alkaloids, isofiliformine ( 1) and cassythic acid ( 3), along with 22 known compounds were isolated from whole herb of Cassytha filiformis. Cassythic acid ( 3), cassythine ( 4), neolitsine ( 7), and dicentrine ( 8) had potent vasorelaxing effects on precontracted rat aortic preparations with mean IC 50 values between 0.08 and 2.48 microM. Compounds 1, 1,2-methylenedioxy-3,10,11-trimethoxyaporphine ( 2), (-)- O-methylflavinatine ( 10), (-)-salutaridine ( 11), isohamnetin-3- O-beta-glucoside, and isohamnetin-3- O-rutinoside exerted moderate vessel-relaxing activities with IC 50 values from 16.50 to 32.81 microM at the test concentrations.
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