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11-Hydroxyhumantenine

CAS# 122590-04-9

11-Hydroxyhumantenine

2D Structure

Catalog No. BCN4863----Order now to get a substantial discount!

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11-Hydroxyhumantenine: 5mg $1150 In Stock
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Quality Control of 11-Hydroxyhumantenine

3D structure

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11-Hydroxyhumantenine

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Chemical Properties of 11-Hydroxyhumantenine

Cas No. 122590-04-9 SDF Download SDF
PubChem ID 5318224 Appearance Powder
Formula C21H26N2O4 M.Wt 370.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC=C1CN(C2CC3(C4CC1C2CO4)C5=C(C=C(C=C5)O)N(C3=O)OC)C
Standard InChIKey VYZFRSLZSBLYIC-UUILKARUSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 11-Hydroxyhumantenine

The herbs of Gelsemium elegans

Biological Activity of 11-Hydroxyhumantenine

DescriptionStandard reference

Protocol of 11-Hydroxyhumantenine

Structure Identification
Helvetica Chimica Acta.2009 Sep;92(9):1889–1894.

Two New 11-Hydroxy-Substituted Gelsedine-Type Indole Alkaloids from the Stems of Gelsemium elegans.[Reference: WebLink]


METHODS AND RESULTS:
Two new 11-hydroxy-substituted gelsedine-type indole alkaloids, named 11,14-dihydroxygelsenicine (1) and 11-hydroxygelsenicine (2), together with six known alkaloids, i.e., koumine, gelsemine, 14-hydroxygelsenicine, 11-Hydroxyhumantenine, gelsenicine, and (19Z)-akuammidine, were isolated from the EtOH extract of the stems of Gelsemium elegansbenth. Their structures were determined mainly by means of spectroscopic analyses including HR-ESI-MS and 2D-NMR (HSQC, HMBC, 1H,1H-COSY).
CONCLUSIONS:
The configuration of 1 was confirmed by X-ray-diffraction analysis.

11-Hydroxyhumantenine Dilution Calculator

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11-Hydroxyhumantenine Molarity Calculator

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Preparing Stock Solutions of 11-Hydroxyhumantenine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6991 mL 13.4953 mL 26.9906 mL 53.9811 mL 67.4764 mL
5 mM 0.5398 mL 2.6991 mL 5.3981 mL 10.7962 mL 13.4953 mL
10 mM 0.2699 mL 1.3495 mL 2.6991 mL 5.3981 mL 6.7476 mL
50 mM 0.054 mL 0.2699 mL 0.5398 mL 1.0796 mL 1.3495 mL
100 mM 0.027 mL 0.135 mL 0.2699 mL 0.5398 mL 0.6748 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 11-Hydroxyhumantenine

Two New 11-Hydroxy-Substituted Gelsedine-Type Indole Alkaloids from the Stems of Gelsemium elegans.

Helvetica Chimica Acta.2009 Sep;92(9):1889–1894.

Two new 11-hydroxy-substituted gelsedine-type indole alkaloids, named 11,14-dihydroxygelsenicine (1) and 11-hydroxygelsenicine (2), together with six known alkaloids, i.e., koumine, gelsemine, 14-hydroxygelsenicine, 11-Hydroxyhumantenine, gelsenicine, and (19Z)-akuammidine, were isolated from the EtOH extract of the stems of Gelsemium elegansbenth. Their structures were determined mainly by means of spectroscopic analyses including HR-ESI-MS and 2D-NMR (HSQC, HMBC, 1H,1H-COSY). The configuration of 1 was confirmed by X-ray-diffraction analysis.

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