Gelomulide A

CAS# 122537-59-1

Gelomulide A

Catalog No. BCN6580----Order now to get a substantial discount!

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Gelomulide A: 5mg $799 In Stock
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Quality Control of Gelomulide A

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Chemical structure

Gelomulide A

3D structure

Chemical Properties of Gelomulide A

Cas No. 122537-59-1 SDF Download SDF
PubChem ID 14286064 Appearance Powder
Formula C22H30O5 M.Wt 374.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1S,3R,8R,10S,11R,14S,16S)-5,11,15,15-tetramethyl-6-oxo-2,7-dioxapentacyclo[8.8.0.01,3.04,8.011,16]octadec-4-en-14-yl] acetate
SMILES CC1=C2C(CC3C4(CCC(C(C4CCC35C2O5)(C)C)OC(=O)C)C)OC1=O
Standard InChIKey FEAJKDLCGUYWFP-YNWCVRRFSA-N
Standard InChI InChI=1S/C22H30O5/c1-11-17-13(26-19(11)24)10-15-21(5)8-7-16(25-12(2)23)20(3,4)14(21)6-9-22(15)18(17)27-22/h13-16,18H,6-10H2,1-5H3/t13-,14-,15+,16+,18-,21-,22+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gelomulide A

The leaves of Suregada glomerulata(Bl.) Baill.

Biological Activity of Gelomulide A

DescriptionStandard reference

Protocol of Gelomulide A

Structure Identification
Journal of Shenyang Pharmaceutical University,2013,30(9):669-73.

Isolation and identification of diterpenoids from Suregada glomerulata (Bl.) Baill[Reference: WebLink]

To isolate and identify the chemical constituents from Suregadaglomerulata(Bl.)Baill.
METHODS AND RESULTS:
The compounds were isolated by chromatography of silica gel,Sephadex LH20,ODS column and semi-preparative C18 HPLC,their structures were identified on the basis of physicochemical data and spectroscopic analysis. Twelve compounds were isolated and their structures were identified as 3α,17-dihydroxy-ent-pimara-8(14),15-diene(1),3β-acetoxy-1-one-8β,14α-epoxy-13,15-abiatene-16,12-olide(2),gelomulide D(3),gelomulide E(4),helioscopinolide C(5),3β-acetoxy-8β,14α-dihydroxy-1-one-13,15-abiatene-16,12-olide(6),3β,6β-diacetoxy-1-one8β,14α-epoxy-13,15-abiatene-16,12-olide(7),Gelomulide A(8),gelomulide G(9),helioscopinolide A(10),helioscopinolide D(11)and helioscopinolide B(12).
CONCLUSIONS:
Compound 1 is reported fromSuregada genus for the first time and compounds 2-8 are isolated from this plant for the first time.

Gelomulide A Dilution Calculator

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Gelomulide A Molarity Calculator

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Preparing Stock Solutions of Gelomulide A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6702 mL 13.3511 mL 26.7023 mL 53.4045 mL 66.7557 mL
5 mM 0.534 mL 2.6702 mL 5.3405 mL 10.6809 mL 13.3511 mL
10 mM 0.267 mL 1.3351 mL 2.6702 mL 5.3405 mL 6.6756 mL
50 mM 0.0534 mL 0.267 mL 0.534 mL 1.0681 mL 1.3351 mL
100 mM 0.0267 mL 0.1335 mL 0.267 mL 0.534 mL 0.6676 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Gelomulide A

Isolation and identification of diterpenoids from Suregada glomerulata (Bl.) Baill

Journal of Shenyang Pharmaceutical University,2013,30(9):669-73.

To isolate and identify the chemical constituents from Suregadaglomerulata(Bl.)Baill.Methods The compounds were isolated by chromatography of silica gel,Sephadex LH20,ODS column and semi-preparative C18 HPLC,their structures were identified on the basis of physicochemical data and spectroscopic analysis.Results Twelve compounds were isolated and their structures were identified as 3α,17-dihydroxy-ent-pimara-8(14),15-diene(1),3β-acetoxy-1-one-8β,14α-epoxy-13,15-abiatene-16,12-olide(2),gelomulide D(3),gelomulide E(4),helioscopinolide C(5),3β-acetoxy-8β,14α-dihydroxy-1-one-13,15-abiatene-16,12-olide(6),3β,6β-diacetoxy-1-one8β,14α-epoxy-13,15-abiatene-16,12-olide(7),Gelomulide A(8),gelomulide G(9),helioscopinolide A(10),helioscopinolide D(11)and helioscopinolide B(12).Conclusions Compound 1 is reported fromSuregada genus for the first time and compounds 2-8 are isolated from this plant for the first time.

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