Gentiside B

CAS# 1225022-67-2

Gentiside B

Catalog No. BCN7301----Order now to get a substantial discount!

Product Name & Size Price Stock
Gentiside B: 5mg $799 In Stock
Gentiside B: 10mg Please Inquire In Stock
Gentiside B: 20mg Please Inquire Please Inquire
Gentiside B: 50mg Please Inquire Please Inquire
Gentiside B: 100mg Please Inquire Please Inquire
Gentiside B: 200mg Please Inquire Please Inquire
Gentiside B: 500mg Please Inquire Please Inquire
Gentiside B: 1000mg Please Inquire Please Inquire

Quality Control of Gentiside B

Number of papers citing our products

Chemical structure

Gentiside B

3D structure

Chemical Properties of Gentiside B

Cas No. 1225022-67-2 SDF Download SDF
PubChem ID 46229236 Appearance Powder
Formula C30H52O4 M.Wt 476.74
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(20S)-20-methyldocosyl] 2,3-dihydroxybenzoate
SMILES CCC(C)CCCCCCCCCCCCCCCCCCCOC(=O)C1=C(C(=CC=C1)O)O
Standard InChIKey FIEXPCXAWNKDMT-SANMLTNESA-N
Standard InChI InChI=1S/C30H52O4/c1-3-26(2)22-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-25-34-30(33)27-23-21-24-28(31)29(27)32/h21,23-24,26,31-32H,3-20,22,25H2,1-2H3/t26-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gentiside B

The whole plants of Gentiana rigescens Franch.

Biological Activity of Gentiside B

Description1. Gentiside B is a potent inducer of neurite outgrowth on PC12 cells, it shows a significant neuritogenic activity at 30 microM against PC12 cells that is comparable to that seen for the best nerve growth factor (NGF) concentration of 40 ng/mL.

Gentiside B Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Gentiside B Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Gentiside B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0976 mL 10.4879 mL 20.9758 mL 41.9516 mL 52.4395 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL 8.3903 mL 10.4879 mL
10 mM 0.2098 mL 1.0488 mL 2.0976 mL 4.1952 mL 5.2439 mL
50 mM 0.042 mL 0.2098 mL 0.4195 mL 0.839 mL 1.0488 mL
100 mM 0.021 mL 0.1049 mL 0.2098 mL 0.4195 mL 0.5244 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Gentiside B

Gentisides C-K: nine new neuritogenic compounds from the traditional Chinese medicine Gentiana rigescens Franch.[Pubmed:20813533]

Bioorg Med Chem. 2010 Oct 1;18(19):6995-7000.

Nine new alkyl 2,3-dihydroxybenzoates, gentisides C-K, were isolated from the traditional Chinese medicine Gentiana rigescens Franch. Their structures and stereochemistry were elucidated by spectroscopic methods, and comparison of the specific rotation with that of the Gentiside B. These metabolites are additional members of the gentisides which belong to a novel class of neuritogenic compounds. They are structurally different from one another because they possess varying alkyl chain lengths, with or without an isobutyl or isopropyl group at the end of the alkyl chain. These compounds are potent inducers of neurite outgrowth on PC12 cells. The gentiside C possessing the shortest alkyl chain length exhibited the highest neuritogenic activity among all of the gentisides. Gentiside C showed a significant neuritogenic activity at 1 muM against PC12 cells comparable to that seen for the best nerve growth factor (NGF) concentration of 40 ng/mL. In addition, evident neuritogenic activity was observed in the cells when treated with gentiside C at a concentration as low as 0.03 muM. The structure-activity relationships within the gentisides A-K revealed that alkyl chain length is important for the activity, but structure diversity at the end of the alkyl chain is not.

Keywords:

Gentiside B,1225022-67-2,Natural Products, buy Gentiside B , Gentiside B supplier , purchase Gentiside B , Gentiside B cost , Gentiside B manufacturer , order Gentiside B , high purity Gentiside B

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: