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15-Isopimarene-8,18-diol

CAS# 73002-86-5

15-Isopimarene-8,18-diol

Catalog No. BCN4287----Order now to get a substantial discount!

Product Name & Size Price Stock
15-Isopimarene-8,18-diol: 5mg Please Inquire In Stock
15-Isopimarene-8,18-diol: 10mg Please Inquire In Stock
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Chemical structure

15-Isopimarene-8,18-diol

3D structure

Chemical Properties of 15-Isopimarene-8,18-diol

Cas No. 73002-86-5 SDF Download SDF
PubChem ID 101465555 Appearance Powder
Formula C20H34O2 M.Wt 306.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Synonyms 8-Hydroxysandaracopimarinol
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,4aS,4bR,7S,8aR,10aR)-7-ethenyl-1-(hydroxymethyl)-1,4a,7-trimethyl-2,3,4,4b,5,6,8,9,10,10a-decahydrophenanthren-8a-ol
SMILES CC1(CCC2C3(CCCC(C3CCC2(C1)O)(C)CO)C)C=C
Standard InChIKey RIQATFSOVFFVRX-DWIKVQACSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 15-Isopimarene-8,18-diol

The branch of Platycladus orientalis

15-Isopimarene-8,18-diol Dilution Calculator

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15-Isopimarene-8,18-diol Molarity Calculator

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Preparing Stock Solutions of 15-Isopimarene-8,18-diol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2626 mL 16.3132 mL 32.6264 mL 65.2529 mL 81.5661 mL
5 mM 0.6525 mL 3.2626 mL 6.5253 mL 13.0506 mL 16.3132 mL
10 mM 0.3263 mL 1.6313 mL 3.2626 mL 6.5253 mL 8.1566 mL
50 mM 0.0653 mL 0.3263 mL 0.6525 mL 1.3051 mL 1.6313 mL
100 mM 0.0326 mL 0.1631 mL 0.3263 mL 0.6525 mL 0.8157 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 15-Isopimarene-8,18-diol

Active principles of Tetradenia riparia. I. Antimicrobial activity of 8(14),15-sandaracopimaradiene-7 alpha,18-diol.[Pubmed:3807389]

J Ethnopharmacol. 1986 Sep;17(3):269-75.

Tetradenia riparia is one of the most popular medicinal plants in Rwanda. Previously, several new substances have been isolated from the leaves of this plant, including a new diterpene diol, i.e. 8(14),15-sandaracopimaradiene-7 alpha,18-diol. This new diterpene diol exhibits significant antimicrobial activity against several bacteria and fungi. The minimum inhibitory concentration (MIC) of the substance for microorganisms which were inhibited ranged from 6.25 to 100 micrograms/ml.

Acute and neurotoxicity of two structurally related acetylenic compounds: 5,7,11-dodecatriyn-1-ol and 5,7,11,13-octadecatetrayne-1,18-diol.[Pubmed:3356863]

J Appl Toxicol. 1988 Feb;8(1):35-42.

Two structurally related acetylenic compounds, 5,7,11-Dodecatriyn-1-ol, (Compound A), and 5,7,11,13-Octadecatetrayne-1,18-Diol (Compound B), were evaluated in a tier I toxicology testing program as part of an ongoing research and development program. This battery of acute tests included acute oral, guinea pig maximization, photosensitization, dermal irritation, Ames and multiple genetic endpoint and a 2 week oral fetotoxicity study. Compound A was found to have an oral LD50 of 0.25 ml/kg, be an extreme dermal sensitizer, a mild dermal irritant (PDII of 1.7), and not mutagenic or fetotoxic in the tests employed. Compound B had an oral LD50 greater than 4 g/kg, was a moderate dermal sensitizer and mild dermal irritant (PDII of 1.4), was not mutagenic in the Ames test but weakly increased the incidence of SCEs and gene mutations in Chinese Hamster Ovary cells, and was not fetotoxic. Neither compound was found to be a photosensitizer, but during the course of the photosensitization study Compound A was found to cause neuromuscular signs (including hind limb paralysis) and a bilateral necrosis of the medulla oblongata in female guinea pigs. A similar lesion was found in female rats receiving a single oral dose of 0.25 ml/kg and in nonpregnant females dosed daily for two weeks at 0.03 ml/kg. Compound B was not found to produce any of these neurologic effects.

ent-5alpha,3,15-Dioxodolabr-4(18)-ene-16,18-diol.[Pubmed:21589075]

Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 23;66(Pt 11):o2897-8.

The title compound, C(20)H(30)O(4), is a dolabrane diterpenoid isolated from Ceriops tagal, in which one of the three fused cyclo-hexane rings adopts a half-chair conformation and the other two are in the standard chair conformations. The hy-droxy-methyl-idene substituent is attached to the half-chair cyclo-hexane. An intra-molecular O-Hcdots, three dots, centeredO hydrogen bond generate an S(6) ring motif. In the crystal, mol-ecules are arranged into screw chains along the [001] direction. The crystal is stabilized by O-Hcdots, three dots, centeredO hydrogen bonds and weaker C-Hcdots, three dots, centeredO inter-actions.

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