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15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

CAS# 1039673-32-9

15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

Catalog No. BCN1637----Order now to get a substantial discount!

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15-Nor-14-oxolabda-8(17),12-dien-18-oic acid: 5mg $989 In Stock
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Quality Control of 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

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Chemical structure

15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

3D structure

Chemical Properties of 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

Cas No. 1039673-32-9 SDF Download SDF
PubChem ID 91885095 Appearance Powder
Formula C19H28O3 M.Wt 304.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,4aR,5S,8aR)-1,4a-dimethyl-6-methylidene-5-[(E)-3-methyl-4-oxobut-2-enyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid
SMILES CC(=CCC1C(=C)CCC2C1(CCCC2(C)C(=O)O)C)C=O
Standard InChIKey NBGCWDAYASHSEK-YDZYAZLNSA-N
Standard InChI InChI=1S/C19H28O3/c1-13(12-20)6-8-15-14(2)7-9-16-18(15,3)10-5-11-19(16,4)17(21)22/h6,12,15-16H,2,5,7-11H2,1,3-4H3,(H,21,22)/b13-6+/t15-,16+,18+,19+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

The barks of Pinus yunnanensis

Biological Activity of 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

Description1. 15-Nor-14-oxolabda-8(17),12 E-diene-18-oic acid shows antibacterial (Propionibacterium acnes) and antifungal activities.
TargetsAntifection

15-Nor-14-oxolabda-8(17),12-dien-18-oic acid Dilution Calculator

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15-Nor-14-oxolabda-8(17),12-dien-18-oic acid Molarity Calculator

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Preparing Stock Solutions of 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2852 mL 16.4258 mL 32.8515 mL 65.703 mL 82.1288 mL
5 mM 0.657 mL 3.2852 mL 6.5703 mL 13.1406 mL 16.4258 mL
10 mM 0.3285 mL 1.6426 mL 3.2852 mL 6.5703 mL 8.2129 mL
50 mM 0.0657 mL 0.3285 mL 0.657 mL 1.3141 mL 1.6426 mL
100 mM 0.0329 mL 0.1643 mL 0.3285 mL 0.657 mL 0.8213 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid

Labdane-type diterpenes active against acne from pine cones (Pinus densiflora).[Pubmed:18484541]

Planta Med. 2008 Mar;74(4):449-52.

Bioassay-guided extraction and fractionation of the aqueous methanolic extract of the cones of Pinus densiflora (Pinaceae) afforded one new labdane-type diterpene aldehyde, 15-nor-14-oxolabda-8(17),12 E-diene-18-oic acid, along with eight known diterpenes. Their structures were elucidated using spectroscopic methods as well as by comparison with previously reported data. The isolates showed antibacterial (Propionibacterium acnes) and antifungal activities.

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