2-Acetyl-5-bromothiopheneCAS# 5370-25-2 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 5370-25-2 | SDF | Download SDF |
| PubChem ID | 79335 | Appearance | Powder |
| Formula | C6H5BrOS | M.Wt | 205 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-(5-bromothiophen-2-yl)ethanone | ||
| SMILES | CC(=O)C1=CC=C(S1)Br | ||
| Standard InChIKey | IGBZCOWXSCWSHO-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C6H5BrOS/c1-4(8)5-2-3-6(7)9-5/h2-3H,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
2-Acetyl-5-bromothiophene Dilution Calculator
2-Acetyl-5-bromothiophene Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.878 mL | 24.3902 mL | 48.7805 mL | 97.561 mL | 121.9512 mL |
| 5 mM | 0.9756 mL | 4.878 mL | 9.7561 mL | 19.5122 mL | 24.3902 mL |
| 10 mM | 0.4878 mL | 2.439 mL | 4.878 mL | 9.7561 mL | 12.1951 mL |
| 50 mM | 0.0976 mL | 0.4878 mL | 0.9756 mL | 1.9512 mL | 2.439 mL |
| 100 mM | 0.0488 mL | 0.2439 mL | 0.4878 mL | 0.9756 mL | 1.2195 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Mexiletine HCl
Catalog No.:BCC4677
CAS No.:5370-01-4
- beta-Amyrenonol methylthiomethyl ether
Catalog No.:BCN3354
CAS No.:
- N-Acetyl-m-toluidine
Catalog No.:BCC9083
CAS No.:537-92-8
- Soyasaponin Be Methyl Ester
Catalog No.:BCN5925
CAS No.:117210-13-6
- N-Acetyl-L-tyrosine
Catalog No.:BCC9082
CAS No.:537-55-3
- Pterostilbene
Catalog No.:BCN2539
CAS No.:537-42-8
- Chlorophorin
Catalog No.:BCN3288
CAS No.:537-41-7
- Convolvine
Catalog No.:BCN1904
CAS No.:537-30-4
- Isoporoidine
Catalog No.:BCN1890
CAS No.:537-28-0
- Tropacocaine
Catalog No.:BCN1934
CAS No.:537-26-8
- Diperodon HCl
Catalog No.:BCC3766
CAS No.:537-12-2
- 3-Acetyl-5-Hydroxymethyl-7-Hydroxycoumarin
Catalog No.:BCC9201
CAS No.:53696-74-5
- BML-210(CAY10433)
Catalog No.:BCC6479
CAS No.:537034-17-6
- Tubacin
Catalog No.:BCC2428
CAS No.:537049-40-4
- Carprofen
Catalog No.:BCC4645
CAS No.:53716-49-7
- Oxfendazole
Catalog No.:BCC4817
CAS No.:53716-50-0
- Bruceantinol
Catalog No.:BCN7616
CAS No.:53729-52-5
- Luteolin-7-O-glucoside
Catalog No.:BCN5388
CAS No.:5373-11-5
- Neorauflavane
Catalog No.:BCN4791
CAS No.:53734-74-0
- Neorauflavene
Catalog No.:BCN4848
CAS No.:53734-75-1
- Lyclaninol
Catalog No.:BCN5710
CAS No.:53755-76-3
- Lycernuic acid A
Catalog No.:BCN5711
CAS No.:53755-77-4
- UF 010
Catalog No.:BCC6478
CAS No.:537672-41-6
- CP-724714
Catalog No.:BCC1188
CAS No.:537705-08-1
SYNTHESIS OF NOVEL BITHIOPHENE-SUBSTITUTED HETEROCYCLES BEARING CARBONITRILE GROUPS.[Pubmed:21546984]
Synth Commun. 2011 Jan 1;41(3):319-330.
Symmetrical and unsymmetrical bithiophene-substituted heterocycles bearing carbonitriles including imidazo[1,2-a]pyridine, benzimidazole, and pyridine derivatives have been synthesized via different synthetic protocols. The bithiophene bis-imidazo[1,2-a]pyridine derivatives 3a,b were achieved in three steps starting from 2-Acetyl-5-bromothiophene. Suzuki coupling reaction of 2a with 5-formylthiophen-2-ylboronic acid forms the formyl derivative 5, which by condensation with 3,4-diaminobenzonitrile in the presence of sodium bisulfite furnishes the unsymmetrical bithiophene derivative 6. The bis-benzimidazole derivative 8 was obtained via hexabutylditin-mediated homocoupling of 5-bromothiophene-2-carboxaldehyde, while the benzimidazole derivatives 12a,b were prepared via the formyl derivatives 11a,b, a product of Velsmier formylation reaction of 10a,b. Two synthetic protocols for the aryl/hetaryl-2,2'-bithiophene derivative 14 have also been presented. In addition, the guanyl hydrazones of bithiophenes, 16 and 17, were prepared from bis(tri-n-butylstannyl)-2,2'-bithiophene through a Stille coupling reaction followed by a condensation step.
Use of phosphonyl carbanions in the synthesis of anti-inflammatory active phosphorus-containing fused heterocycles and relevance phosphonates.[Pubmed:20817324]
Eur J Med Chem. 2010 Nov;45(11):5217-24.
The reaction of Horner-Emmons reactant carbanions with 2-acetyl-5-methyl furan 1 and 2-Acetyl-5-bromothiophene 9 resulted in phosphorus-containing fused bicyclic 5,5-membered and 5,6-membered systems 5a-c and 12a-c, respectively, as major reaction products along with minor ( approximately 20%) amounts of phosphorylated heterocycles 3a-c and 10a-c. Further treatment of bromo-substituted bicyclic systems 12a-c with the corresponding carbanion proceeded as a substitution of bromine for the residue of the Horner-Emmons reactant to afford compounds 13a-c bearing endo- and exocyclic phosphorus atoms. Reaction of diethyl vinylphosphonate with 5-methylfuran 1 and 5-bromothiophene 9 provided spirofuran 8 as a sole reaction product and (5H-thieno[3,2-d]oxaphosphinin-2-yl)vinylphosphonate 15, respectively. Among the products, at 50 mg/kg dose, 4 compounds showed notable anti-inflammatory activity without toxicity side-effect.
