(2RS)-LotaustralinCAS# 1973415-50-7 |
Quality Control & MSDS
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| Cas No. | 1973415-50-7 | SDF | Download SDF |
| PubChem ID | 23638286 | Appearance | Powder |
| Formula | C11H19NO6 | M.Wt | 261.27 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutanenitrile | ||
| SMILES | CCC(C)(C#N)OC1C(C(C(C(O1)CO)O)O)O | ||
| Standard InChIKey | WEWBWVMTOYUPHH-GXUZYPEDSA-N | ||
| Standard InChI | InChI=1S/C11H19NO6/c1-3-11(2,5-12)18-10-9(16)8(15)7(14)6(4-13)17-10/h6-10,13-16H,3-4H2,1-2H3/t6-,7-,8+,9-,10+,11?/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | (2RS)-Lotaustralin is a natural product from Rhodiola rosea L. |
| In vitro | Optimization of process parameters of extraction of lotaustralin from the roots of Rhodiola rosea L using supercritical CO2 plus modifier.[Reference: WebLink]Toxicological & Environmental Chemistry Reviews, 2016, 98(7):727-735.Lotaustralin((2RS)-Lotaustralin) from the root of Rhodiola rosea L was extracted using supercritical carbon dioxide with methanol as modifier.
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(2RS)-Lotaustralin Dilution Calculator
(2RS)-Lotaustralin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.8275 mL | 19.1373 mL | 38.2746 mL | 76.5492 mL | 95.6865 mL |
| 5 mM | 0.7655 mL | 3.8275 mL | 7.6549 mL | 15.3098 mL | 19.1373 mL |
| 10 mM | 0.3827 mL | 1.9137 mL | 3.8275 mL | 7.6549 mL | 9.5686 mL |
| 50 mM | 0.0765 mL | 0.3827 mL | 0.7655 mL | 1.531 mL | 1.9137 mL |
| 100 mM | 0.0383 mL | 0.1914 mL | 0.3827 mL | 0.7655 mL | 0.9569 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Optimization of process parameters of extraction of lotaustralin from the roots of Rhodiola rosea L using supercritical CO2 plus modifier.
Toxicological & Environmental Chemistry Reviews, 2016, 98(7):727-735.
Lotaustralin((2RS)-Lotaustralin) from the root of Rhodiola rosea L was extracted using supercritical carbon dioxide with methanol as modifier. Response surface methodology using Box–Behnken experimental design was utilized to explore parameters for supercritical carbon dioxide extraction. The effects of various values of temperatures (50–70 °C), pressures (200--400 bar), and percentages of methanol modifier (80%–100%) on the extraction yields of lotaustralin were evaluated. Extract identification was performed using high-performance liquid chromatography. The experimental data obtained were fitted to second-order polynomial equations and assessed using analysis of variance. The highest yields predicted from the experiments were 2.05 g kg−1 lotaustralin at the optimal values, i.e. temperature 65 °C, pressure 316 bar, 88% methanol modifier at a flow rate of 0.4 mL min−1, and dynamic extraction time 90 min.
