Isocudraniaxanthone ACAS# 197447-26-0 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 197447-26-0 | SDF | Download SDF |
| PubChem ID | 10687703 | Appearance | Powder |
| Formula | C18H16O6 | M.Wt | 328.32 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,5,6-tetrahydroxy-4-(2-methylbut-3-en-2-yl)xanthen-9-one | ||
| SMILES | CC(C)(C=C)C1=C(C=C(C2=C1OC3=C(C2=O)C=CC(=C3O)O)O)O | ||
| Standard InChIKey | GXZSMOZDSUSQHH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C18H16O6/c1-4-18(2,3)13-11(21)7-10(20)12-14(22)8-5-6-9(19)15(23)16(8)24-17(12)13/h4-7,19-21,23H,1H2,2-3H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Isocudraniaxanthone A may have antimalarial activity. |
| Targets | Antifection |
Isocudraniaxanthone A Dilution Calculator
Isocudraniaxanthone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.0458 mL | 15.229 mL | 30.4581 mL | 60.9162 mL | 76.1452 mL |
| 5 mM | 0.6092 mL | 3.0458 mL | 6.0916 mL | 12.1832 mL | 15.229 mL |
| 10 mM | 0.3046 mL | 1.5229 mL | 3.0458 mL | 6.0916 mL | 7.6145 mL |
| 50 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.2183 mL | 1.5229 mL |
| 100 mM | 0.0305 mL | 0.1523 mL | 0.3046 mL | 0.6092 mL | 0.7615 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- (2RS)-Lotaustralin
Catalog No.:BCN7848
CAS No.:1973415-50-7
- 11-Dehydroxygrevilloside B
Catalog No.:BCN4867
CAS No.:197307-49-6
- Glycyrrhiza flavonol A
Catalog No.:BCN7995
CAS No.:197304-01-1
- Methiothepin maleate
Catalog No.:BCC6706
CAS No.:19728-88-2
- Z-Thr-OH
Catalog No.:BCC2751
CAS No.:19728-63-3
- Gap 26
Catalog No.:BCC1032
CAS No.:197250-15-0
- NTR 368
Catalog No.:BCC5872
CAS No.:197230-90-3
- Delta-9-Tetrahydrocannabinol
Catalog No.:BCN8074
CAS No.:1972-08-3
- Pseudopalmatine
Catalog No.:BCN4866
CAS No.:19716-66-6
- 8-Oxycoptisine
Catalog No.:BCN3136
CAS No.:19716-61-1
- Oxyepiberberine
Catalog No.:BCN2882
CAS No.:19716-60-0
- 8-Oxypalmatine
Catalog No.:BCN3137
CAS No.:19716-59-7
- Latisxanthone C
Catalog No.:BCN7346
CAS No.:197447-32-8
- Boc-Cys(Acm)-OH
Catalog No.:BCC3374
CAS No.:19746-37-3
- 2-Methyl-4-nitrobenzoic acid
Catalog No.:BCC8580
CAS No.:1975-51-5
- TRAM 39
Catalog No.:BCC8038
CAS No.:197525-99-8
- Calystegine A7
Catalog No.:BCN1885
CAS No.:197565-90-5
- Calystegine B5
Catalog No.:BCN1883
CAS No.:197565-91-6
- Fmoc-β-HomoTrp(Boc)-OH
Catalog No.:BCC2625
CAS No.:197632-75-0
- Fmoc-D-β-HomoTrp(Boc)-OH
Catalog No.:BCC2624
CAS No.:197632-75-1
- Fmoc-N-Me-Ser(tBu)-OH
Catalog No.:BCC3353
CAS No.:197632-77-2
- Tigecycline hydrochloride
Catalog No.:BCC4228
CAS No.:197654-04-9
- Mesna
Catalog No.:BCC3811
CAS No.:19767-45-4
- Loxapine
Catalog No.:BCC4026
CAS No.:1977-10-2
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii.[Pubmed:15474559]
Life Sci. 2004 Nov 5;75(25):3077-85.
The antimalarial activity of 22 xanthones against chloroquino-resistant strains of Plasmodium falciparum was evaluated. Natural caloxanthone C (1), demethylcalabaxanthone (2), calothwaitesixanthone (3), calozeyloxanthone (4), dombakinaxanthone (5), macluraxanthone (6), and 6-deoxy-gamma-mangostin (7) were isolated from Calophyllum caledonicum. 1,6-dihydroxyxanthone (8), pancixanthone A (9), isocudraniaxanthone B (10), Isocudraniaxanthone A (11), 2-deprenylrheediaxanthone B (12) and 1,4,5-trihydroxyxanthone (13) were isolated from Garcinia vieillardii. Moreover, synthetic compounds (14-22) are analogues or intermediates of xanthones purified from Calophyllum caledonicum (Oger J.M., Morel C., Helesbeux J.J., Litaudon M., Seraphin D., Dartiguelongue C., Larcher G., Richomme P., Duval O. 2003. First 2-Hydroxy-3-Methylbut-3-Enyl substituted xanthones isolated from Plants: structure elucidation, synthesis and antifungal activity. Natural Product Research 17(3), 195-199; Helesbeux J.J., Duval O., Dartiguelongue C., Seraphin D., Oger J.M., Richomme P., 2004. Synthesis of 2-hydroxy-3-methylbut-3-enyl substituted coumarins and xanthones as natural products. Application of the Schenck ene reaction of singlet oxygen with ortho-prenylphenol precursors. Tetrahedron 60(10), 2293-2300). The relationship between antimalarial activity and molecular structure of xanthones has also been explored. The most potent xanthones (2), (3) and (7) (IC50 = c.a. 1.0 microg/mL) are 1,3,7 trioxygenated and prenylated on the positions 2 and 8.
Indonesian medicinal plants. XXI. Inhibitors of Na+/H+ exchanger from the bark of Erythrina variegata and the roots of Maclura cochinchinensis.[Pubmed:9353889]
Chem Pharm Bull (Tokyo). 1997 Oct;45(10):1615-9.
Through bioassay-guided separation of the methanol extracts of Indonesian medicinal plants, three inhibitors of the Na+/H+ exchange system, erythrinin B (2), euchrenone b10 (3), and 1,3,5-trihydroxy-4-(3-methylbut-2-enyl)xanthen-9-one (4), were isolated from the bark of Erythrina variegata (Fabaceae) (for 2) and the roots of Maclura cochinchinensis (Moraceae) (for 2, 3, 4). Compounds 2, 3, and 4 significantly inhibited the Na+/H+ exchange system of arterial smooth muscle cells, with minimum inhibitory concentrations of 1.25, 1.25, and 10 micrograms/ml, respectively. Three new prenylated xanthones named isocudraniaxanthones B (5) and A (7) and isoalvaxanthone (9) were also isolated from M. cochinchinensis and the chemical structures were elucidated on the bases of their chemical and physicochemical properties.
