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3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

CAS# 35738-25-1

3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

Catalog No. BCN6664----Order now to get a substantial discount!

Product Name & Size Price Stock
3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide: 5mg $799 In Stock
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3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide: 200mg Please Inquire Please Inquire
3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide: 500mg Please Inquire Please Inquire
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Quality Control of 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

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Chemical structure

3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

3D structure

Chemical Properties of 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

Cas No. 35738-25-1 SDF Download SDF
PubChem ID 21626351 Appearance Powder
Formula C32H48O5 M.Wt 512.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(1S,2S,4S,5R,6S,9S,11R,14R,15S,18S,23R)-6,10,10,14,15,21,21-heptamethyl-25-oxo-3,24-dioxaheptacyclo[16.5.2.01,15.02,4.05,14.06,11.018,23]pentacosan-9-yl] acetate
SMILES CC(=O)OC1CCC2(C(C1(C)C)CCC3(C2C4C(O4)C56C3(CCC7(C5CC(CC7)(C)C)C(=O)O6)C)C)C
Standard InChIKey RJEUVXAJCYTMIC-LRFNUQPTSA-N
Standard InChI InChI=1S/C32H48O5/c1-18(33)35-21-10-11-28(6)19(27(21,4)5)9-12-29(7)23(28)22-24(36-22)32-20-17-26(2,3)13-15-31(20,25(34)37-32)16-14-30(29,32)8/h19-24H,9-17H2,1-8H3/t19-,20+,21-,22-,23+,24-,28-,29+,30-,31-,32+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

The branches of Eysenhardtia platycarpa.

Biological Activity of 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

DescriptionStandard reference
In vivo

Antihyperglycemic Activity and Chemical Constituents of Eysenhardtia platycarpa[Pubmed: 17190443 ]

J Nat Prod. 2006 Dec;69(12):1687-91.


METHODS AND RESULTS:
The methanolic extracts from branches (BEP) and leaves (LEP) of Eysenhardtia platycarpa significantly decreased the blood glucose levels in normal and streptozotocin (STZ)-induced diabetic rats. One new flavone, (1"R)-5,4',1"-trihydroxy-6,7-(3",3"-dimethylchroman)flavone (1), together with the known compounds 5,7-dihydroxy-6-methyl-8-prenylflavanone (3), 5,7-dihydroxy-8-methyl-6-prenylflavanone (4), 5,7-dihydroxy-6-prenylflavanone (5), 5,7-dihydroxy-8-prenylflavanone (6), 3-O-acetyloleanolic acid (7), oleanolic acid, 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide, lupeol, betulinic acid, beta-sitosterol, beta-sitosteryl beta-D-glucopyranoside, beta-sitosteryl palmitate, and 3-O-methyl-myo-inositol were isolated from BEP. Additionally, one new flavanone, (2S)-4'-O-methyl-6-methyl-8-prenylnaringenin (2), as well as the known compounds 3, 4, 6, 4'-O-methyl-8-prenylnaringenin (8), and 5-hydroxy-7-methoxy-8-prenylflavanone (9) were isolated from LEP.
CONCLUSIONS:
3-O-Acetyloleanolic acid (7), identified as the major constituent of BEP, showed a significant decrease (31 mg/kg of body weight, P < 0.05) in the glucose level of STZ-induced diabetic rats. The obtained results correlate with the traditional use of this species.

3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide Dilution Calculator

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3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide Molarity Calculator

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Preparing Stock Solutions of 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9505 mL 9.7523 mL 19.5046 mL 39.0092 mL 48.7615 mL
5 mM 0.3901 mL 1.9505 mL 3.9009 mL 7.8018 mL 9.7523 mL
10 mM 0.195 mL 0.9752 mL 1.9505 mL 3.9009 mL 4.8761 mL
50 mM 0.039 mL 0.195 mL 0.3901 mL 0.7802 mL 0.9752 mL
100 mM 0.0195 mL 0.0975 mL 0.195 mL 0.3901 mL 0.4876 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 3beta-Acetoxy-11alpha,12alpha-epoxyoleanan-28,13beta-olide

Antihyperglycemic activity and chemical constituents of Eysenhardtia platycarpa.[Pubmed:17190443]

J Nat Prod. 2006 Dec;69(12):1687-91.

The methanolic extracts from branches (BEP) and leaves (LEP) of Eysenhardtia platycarpa significantly decreased the blood glucose levels in normal and streptozotocin (STZ)-induced diabetic rats. One new flavone, (1"R)-5,4',1"-trihydroxy-6,7-(3",3"-dimethylchroman)flavone (1), together with the known compounds 5,7-dihydroxy-6-methyl-8-prenylflavanone (3), 5,7-dihydroxy-8-methyl-6-prenylflavanone (4), 5,7-dihydroxy-6-prenylflavanone (5), 5,7-dihydroxy-8-prenylflavanone (6), 3-O-acetyloleanolic acid (7), oleanolic acid, 3beta-acetoxy-11alpha,12alpha-epoxy-oleanan-28,13beta-olide, lupeol, betulinic acid, beta-sitosterol, beta-sitosteryl beta-D-glucopyranoside, beta-sitosteryl palmitate, and 3-O-methyl-myo-inositol were isolated from BEP. Additionally, one new flavanone, (2S)-4'-O-methyl-6-methyl-8-prenylnaringenin (2), as well as the known compounds 3, 4, 6, 4'-O-methyl-8-prenylnaringenin (8), and 5-hydroxy-7-methoxy-8-prenylflavanone (9) were isolated from LEP. 3-O-Acetyloleanolic acid (7), identified as the major constituent of BEP, showed a significant decrease (31 mg/kg of body weight, P < 0.05) in the glucose level of STZ-induced diabetic rats. The obtained results correlate with the traditional use of this species.

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