8-AcetonyldihydronitidineCAS# 80330-39-8 |
Quality Control & MSDS
3D structure
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| Cas No. | 80330-39-8 | SDF | Download SDF |
| PubChem ID | 10740045 | Appearance | Powder |
| Formula | C24H23NO5 | M.Wt | 405.5 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-(2,3-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-yl)propan-2-one | ||
| SMILES | CC(=O)CC1C2=CC(=C(C=C2C3=C(N1C)C4=CC5=C(C=C4C=C3)OCO5)OC)OC | ||
| Standard InChIKey | OLYNXAXGZUKQDD-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 8-Acetonyldihydronitidine shows antifungal activity . 2. 8-Acetonyldihydronitidine shows significant antibacterial activity against Gram (+/-) bacteria. |
| Targets | Antifection |
8-Acetonyldihydronitidine Dilution Calculator
8-Acetonyldihydronitidine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4661 mL | 12.3305 mL | 24.6609 mL | 49.3218 mL | 61.6523 mL |
| 5 mM | 0.4932 mL | 2.4661 mL | 4.9322 mL | 9.8644 mL | 12.3305 mL |
| 10 mM | 0.2466 mL | 1.233 mL | 2.4661 mL | 4.9322 mL | 6.1652 mL |
| 50 mM | 0.0493 mL | 0.2466 mL | 0.4932 mL | 0.9864 mL | 1.233 mL |
| 100 mM | 0.0247 mL | 0.1233 mL | 0.2466 mL | 0.4932 mL | 0.6165 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antibacterial alkaloids from Zanthoxylum rhoifolium.[Pubmed:12709908]
Planta Med. 2003 Apr;69(4):371-4.
Two new dihydrobenzophenanthridine-type alkaloids, 6-methoxy dioxolo[4',5':4,5]benzo[c] dioxolo[4,5- j]phenanthridine (1) and 2,3,13-trimethoxy-5,11a-dihydro dioxolo[4',5':4,5]benzo[c]phenanthridine (2) were isolated from the stem bark of Zanthoxylum rhoifolium, together with four other previously known benzophenanthridine alkaloids, 6-acetonyldihydronitidine (3) [= 8-Acetonyldihydronitidine], 6-acetonyldihydroavicine (4) [= 8-acetonyldihydroavicine], 6-acetonyldihydrochelerythrine (5) and xanthoxyline (6). The structures were elucidated mainly by spectroscopic methods, including 1D and 2D NMR spectroscopy. For alkaloids 1 and 2 we propose the trivial names rhoifolines A and B. The crude plant extracts and the alkaloids 3, 4 and 6 showed activity against Gram (+/-) bacteria, while the new alkaloids 1 and 2 were inactive.
Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum.[Pubmed:11324918]
Phytochemistry. 2001 Apr;56(8):857-61.
Two benzophenanthrene alkaloids, 8-Acetonyldihydronitidine and 8-acetonyldihydroavicine were isolated from Zanthoxylum tetraspermum stem bark along with liriodenine, sesamin, lichexanthone and (+)-piperitol-gamma,gamma-dimethylallylether. The species endemic to Sri Lanka, Z. caudatum, contained sesamin, savinin, liriodenine, decarine and 8-O-desmethyl-N-nornitidine. 8-Acetonyldihydronitidine and 8-acetonyldihydroavicine showed significant antibacterial activity while the former along with liriodenine was strongly antifungal. Savinin exhibited potent spermicidal activity. Both savinin and sesamin exhibited significant insecticidal activity.
