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7-Acetylscorpioidine

CAS# 80405-17-0

7-Acetylscorpioidine

2D Structure

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Quality Control of 7-Acetylscorpioidine

3D structure

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7-Acetylscorpioidine

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Chemical Properties of 7-Acetylscorpioidine

Cas No. 80405-17-0 SDF Download SDF
PubChem ID 6440656 Appearance Oil
Formula C22H33NO7 M.Wt 423.50
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(7R,8R)-7-acetyloxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-3-methyl-2-[1-[(E)-2-methylbut-2-enoyl]oxyethyl]butanoate
SMILES CC=C(C)C(=O)OC(C)C(C(C)C)(C(=O)OCC1=CCN2C1C(CC2)OC(=O)C)O
Standard InChIKey YYQUGDOAQAPTLK-BUNUPIFCSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of 7-Acetylscorpioidine

Description7-Acetylscorpioidine is a natural product from Myosotis scorpioides, its free bases cause ataxia, lethargy, and death in mice, accounting for the previously described "curare-like" action of the crude alkaloid fraction.
In vivo

Biologically active pyrrolizidine alkaloids from the true forget-me-not, Myosotis scorpioides.[Reference: WebLink]

Journal of Natural Products, 1982 , 45 (3) :358-362.


METHODS AND RESULTS:
Four pyrrolizidine alkaloids have been isolated from the aerial parts of Myosotis scorpioides.
CONCLUSIONS:
They are 7-Acetylscorpioidine (1), scorpioidine (2), symphytine (4), and myoscorpine (5). Their free bases cause ataxia, lethargy, and death in mice, accounting for the previously described "curare-like" action of the crude alkaloid fraction.

7-Acetylscorpioidine Dilution Calculator

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7-Acetylscorpioidine Molarity Calculator

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Preparing Stock Solutions of 7-Acetylscorpioidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3613 mL 11.8064 mL 23.6128 mL 47.2255 mL 59.0319 mL
5 mM 0.4723 mL 2.3613 mL 4.7226 mL 9.4451 mL 11.8064 mL
10 mM 0.2361 mL 1.1806 mL 2.3613 mL 4.7226 mL 5.9032 mL
50 mM 0.0472 mL 0.2361 mL 0.4723 mL 0.9445 mL 1.1806 mL
100 mM 0.0236 mL 0.1181 mL 0.2361 mL 0.4723 mL 0.5903 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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