Abiesinol ACAS# 1190070-88-2 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products

Cas No. | 1190070-88-2 | SDF | Download SDF |
PubChem ID | N/A | Appearance | Powder |
Formula | C30H22O11 | M.Wt | 558.5 |
Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |

Abiesinol A Dilution Calculator

Abiesinol A Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.7905 mL | 8.9526 mL | 17.9051 mL | 35.8102 mL | 44.7628 mL |
5 mM | 0.3581 mL | 1.7905 mL | 3.581 mL | 7.162 mL | 8.9526 mL |
10 mM | 0.1791 mL | 0.8953 mL | 1.7905 mL | 3.581 mL | 4.4763 mL |
50 mM | 0.0358 mL | 0.1791 mL | 0.3581 mL | 0.7162 mL | 0.8953 mL |
100 mM | 0.0179 mL | 0.0895 mL | 0.1791 mL | 0.3581 mL | 0.4476 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |

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Anti-tumor-initiating effects of spiro-biflavonoids from Abies sachalinensis.[Pubmed:20860032]
Chem Biodivers. 2010 Sep;7(9):2303-8.
Cancer chemoprevention, the prevention of cancer by ingestion of chemical agents that reduce the risk of carcinogenesis, is one of the potent ways to reduce morbidity and mortality. We have been searching for cancer chemopreventive agents from the leaves and barks of coniferous trees that have been treated as waste in the forestry industry. We have previously reported the isolation of spiro-biflavonoids, named as abiesinols, and a neolignan from the MeOH extract of the bark of Abies sachalinensis. These compounds were tested for their inhibitory effects on the activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxyhex-3-enamide (NOR 1), a nitric oxide (NO) donor, as a primary screening test for anti-tumor initiators. All compounds tested exhibited potent inhibitory effects on NOR 1 activation. Furthermore, Abiesinol A, bearing a spiro-biflavonoid skeleton, showed remarkable anti-tumor-initiating activity in the in vivo two-stage mouse skin carcinogenesis test using peroxynitrite (ONOO(-); PN) as the initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as the promoter.