Alisol OCAS# 928148-51-0 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 928148-51-0 | SDF | Download SDF |
| PubChem ID | 102004738 | Appearance | Cryst. |
| Formula | C32H48O5 | M.Wt | 512.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1CC(OC2C1=C3C=CC4C5(CCC(=O)C(C5CCC4(C3(C2)C)C)(C)C)C)C(C(C)(C)O)OC(=O)C | ||
| Standard InChIKey | YDONEKYGVGENMF-XEDHJYNPSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Standard reference |
| In vitro | A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.[Pubmed: 16858666]Planta Med. 2006 Aug;72(10):951-4.
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| Structure Identification | Zhongguo Zhong Yao Za Zhi. 2011 Mar;36(6):758-61.Study on discriminating nephrotoxic components in Zexie[Pubmed: 21710746]
To sift and identify the nephrotoxic components in Zexie for controlling the quality of the herb. |
Alisol O Dilution Calculator
Alisol O Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9505 mL | 9.7523 mL | 19.5046 mL | 39.0092 mL | 48.7615 mL |
| 5 mM | 0.3901 mL | 1.9505 mL | 3.9009 mL | 7.8018 mL | 9.7523 mL |
| 10 mM | 0.195 mL | 0.9752 mL | 1.9505 mL | 3.9009 mL | 4.8761 mL |
| 50 mM | 0.039 mL | 0.195 mL | 0.3901 mL | 0.7802 mL | 0.9752 mL |
| 100 mM | 0.0195 mL | 0.0975 mL | 0.195 mL | 0.3901 mL | 0.4876 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.[Pubmed:16858666]
Planta Med. 2006 Aug;72(10):951-4.
A new triterpenoid named Alisol O ( 1) was isolated from the rhizomes of Alisma orientalis, together with six known compounds: alisol A 24-acetate ( 2), 25-anhydroalisol A ( 3), 13 beta,17 beta-epoxyalisol A ( 4), alisol B 23-acetate ( 5), alisol F ( 6), and alisol F 24-acetate ( 7). Based on 1D and 2D-NMR data (HMQC, HMBC, COSY, ROESY), the structure of the new compound was deduced to be 11-dehydroxy-12-dehydroalisol F-24-acetate ( 1). Compounds 2 - 7 exhibited inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with IC (50) values of 2.3, 11.0, 15.4, 14.3, 0.6 and 7.7 microM, and on HBV e antigen (HBeAg) secretion with IC (50) values of 498.1, 17.6, 41.0, 19.9, 8.5 and 5.1 microM, respectively.
[Study on discriminating nephrotoxic components in Zexie].[Pubmed:21710746]
Zhongguo Zhong Yao Za Zhi. 2011 Mar;36(6):758-61.
OBJECTIVE: To sift and identify the nephrotoxic components in Zexie for controlling the quality of the herb. METHOD: The fractions of zexie were prepared by Pre-HPLC, then the nephrotoxicity of the fraction was sifted using LLC-PK1 labelled with fluorescein diacetate and MTT assay. Finally, the compounds in the most obvious nephrotoxic fraction were identified with LC-MS. RESULT: Using MTT and FDA assay, similar results were obtained. Fraction C13 was found to be the most toxic with FDA assay, in which three compounds, alisol C, 16, 23-oxido-alisol B and Alisol O, were detected and characterized by multi -stage mass spectrometric analysis. CONCLUSION: Alisol C, 16, 23-oxido-alisol B and Alisol O in Zexie may cause nephrotoxicity.
