Tenacissoside FCAS# 928151-78-4 |
- Tenacigenoside A
Catalog No.:BCN4458
CAS No.:920502-42-7
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 928151-78-4 | SDF | Download SDF |
| PubChem ID | 91895269 | Appearance | Powder |
| Formula | C35H56O12 | M.Wt | 668.8 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-[(1S,3R,6R,7S,8S,9S,10S,11S,14S,16S)-14-[(2R,4R,5R,6R)-5-[(2S,3R,4R,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]ethanone | ||
| SMILES | CC1C(C(C(C(O1)OC2C(OC(CC2OC)OC3CCC4(C(C3)CCC56C4C(C(C7(C5(O6)CCC7C(=O)C)C)O)O)C)C)O)OC)O | ||
| Standard InChIKey | WGOHWIVFCMYBJP-HCGZSUPLSA-N | ||
| Standard InChI | InChI=1S/C35H56O12/c1-16(36)21-10-13-35-33(21,5)30(40)26(39)29-32(4)11-9-20(14-19(32)8-12-34(29,35)47-35)45-23-15-22(41-6)27(18(3)43-23)46-31-25(38)28(42-7)24(37)17(2)44-31/h17-31,37-40H,8-15H2,1-7H3/t17-,18-,19+,20+,21+,22-,23+,24-,25-,26+,27-,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Standard reference |
| Structure Identification | Biomed Chromatogr. 2014 Feb;28(2):223-30.Simultaneous determination of six C21 steroids of Xiao-Ai-Ping injection in rat plasma by LC-MS/MS.[Pubmed: 24037806]
|
Tenacissoside F Dilution Calculator
Tenacissoside F Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4952 mL | 7.4761 mL | 14.9522 mL | 29.9043 mL | 37.3804 mL |
| 5 mM | 0.299 mL | 1.4952 mL | 2.9904 mL | 5.9809 mL | 7.4761 mL |
| 10 mM | 0.1495 mL | 0.7476 mL | 1.4952 mL | 2.9904 mL | 3.738 mL |
| 50 mM | 0.0299 mL | 0.1495 mL | 0.299 mL | 0.5981 mL | 0.7476 mL |
| 100 mM | 0.015 mL | 0.0748 mL | 0.1495 mL | 0.299 mL | 0.3738 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Alisol O
Catalog No.:BCN3362
CAS No.:928148-51-0
- Golvatinib (E7050)
Catalog No.:BCC4423
CAS No.:928037-13-2
- RAF265
Catalog No.:BCC3677
CAS No.:927880-90-8
- DPNI-caged-GABA
Catalog No.:BCC5957
CAS No.:927866-58-8
- KC7F2
Catalog No.:BCC2434
CAS No.:927822-86-4
- Glochicoccin D
Catalog No.:BCN4471
CAS No.:927812-23-5
- Motolimod (VTX-2337)
Catalog No.:BCC6497
CAS No.:926927-61-9
- Toll-like receptor modulator
Catalog No.:BCC2007
CAS No.:926927-42-6
- Germacrone 4,5-epoxide
Catalog No.:BCN6724
CAS No.:92691-35-5
- Deltatsine
Catalog No.:BCN8106
CAS No.:92631-66-8
- GGsTop
Catalog No.:BCC6187
CAS No.:926281-37-0
- BG45
Catalog No.:BCC6469
CAS No.:926259-99-6
- 3-Chloro-1-(4-octylphenyl)-propanone
Catalog No.:BCN2249
CAS No.:928165-59-7
- Boc-D-Asp-OBzl
Catalog No.:BCC3370
CAS No.:92828-64-3
- MN 64
Catalog No.:BCC6489
CAS No.:92831-11-3
- AS 1892802
Catalog No.:BCC6335
CAS No.:928320-12-1
- IRAK inhibitor 2
Catalog No.:BCC1655
CAS No.:928333-30-6
- PF-03716556
Catalog No.:BCC2084
CAS No.:928774-43-0
- DB07268
Catalog No.:BCC1519
CAS No.:929007-72-7
- Pracinostat (SB939)
Catalog No.:BCC2152
CAS No.:929016-96-6
- GSK461364
Catalog No.:BCC3788
CAS No.:929095-18-1
- 7-Oxo-ganoderic acid Z
Catalog No.:BCN7973
CAS No.:929248-72-6
- LUF 6283
Catalog No.:BCC6318
CAS No.:92933-48-7
- Fmoc-Tyr-OH
Catalog No.:BCC3562
CAS No.:92954-90-0
Simultaneous determination of six C21 steroids of Xiao-Ai-Ping injection in rat plasma by LC-MS/MS.[Pubmed:24037806]
Biomed Chromatogr. 2014 Feb;28(2):223-30.
Xiao-Ai-Ping injection (XAPI) is a traditional Chinese medicine that has been widely used to treat cancer. Modern pharmacological studies have demonstrated that C21 steroids are the main active compounds in XAPI. In this study, a sensitive and specific liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed and validated the first time for simultanenous determination of three isomeric pregnane genins (17beta-tenacigenin B, tenacigenin B and tenacigenin A) and their corresponding glycosides (tenacigenoside A, Tenacissoside F and marsdenoside I) from XAPI in rat plasma. A simple liquid-liquid extraction technique was used after the addition of dexamethasone acetate as internal standard. The chromatography separation of analytes was achieved on an Agilent Zorbax Eclipse XDB-C18 column (3.5 microm, 150 x 3 mm i.d.) using methanol-water as mobile phase in a gradient elution program. Detection was performed in multiple reaction monitoring mode using electrospray ionization in the negative ion mode. The method showed satisfactory linearity over a concentration range 5.00-2000.00 ng/mL for tenacigenin B, tenacigenin A, marsdenoside I and Tenacissoside F (r(2) > 0.99), 10.00-4000.00 ng/mL for 17beta-tenacigenin B and tenacigenoside A (r(2) > 0.99). Intra- and inter-day precisions (valued as relative standard deviation) were <9.00% and accuracies (as relative error) in the range -6.31 to 7.23%. Finally, this validated method was successfully applied to the pharmacokinetic study of XAPI after intravenous administration to rats.
