Alpinoid D

CAS# 1041740-13-9

Alpinoid D

2D Structure

Catalog No. BCN3593----Order now to get a substantial discount!

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Quality Control of Alpinoid D

3D structure

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Alpinoid D

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Chemical Properties of Alpinoid D

Cas No. 1041740-13-9 SDF Download SDF
PubChem ID 38363343 Appearance Powder
Formula C20H20O3 M.Wt 308.4
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-methoxy-4-[[5-(2-phenylethyl)furan-2-yl]methyl]phenol
SMILES COC1=C(C=CC(=C1)CC2=CC=C(O2)CCC3=CC=CC=C3)O
Standard InChIKey FQYPVFASDPWNIJ-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Alpinoid D

The rhizomes of Alpinia officinarum Hance

Biological Activity of Alpinoid D

DescriptionStandard reference
In vitro

New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum.[Pubmed: 18484537]

Planta Med. 2008 Mar;74(4):427-31.


METHODS AND RESULTS:
Bioassay-guided fractionation of the cytotoxic MeOH extract from the rhizomes of Alpinia officinarum Hance led to the isolation of two new diarylheptanoids named Alpinoid D (1) and E (2), together with fifteen known diarylheptanoids (3 - 17). The structures of compounds Alpinoid D and 2 were elucidated on the basis of spectroscopic data and chemical evidence. The cytotoxic activity of the isolated diarylheptanoids was evaluated against the IMR-32 human neuroblastoma cell line.
CONCLUSIONS:
Among the tested compounds, 11, 12 and 14 exhibited the most potent activities with IC (50) values of 0.83, 0.23 and 0.11 microM, respectively.

Alpinoid D Dilution Calculator

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Alpinoid D Molarity Calculator

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Preparing Stock Solutions of Alpinoid D

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2425 mL 16.2127 mL 32.4254 mL 64.8508 mL 81.0636 mL
5 mM 0.6485 mL 3.2425 mL 6.4851 mL 12.9702 mL 16.2127 mL
10 mM 0.3243 mL 1.6213 mL 3.2425 mL 6.4851 mL 8.1064 mL
50 mM 0.0649 mL 0.3243 mL 0.6485 mL 1.297 mL 1.6213 mL
100 mM 0.0324 mL 0.1621 mL 0.3243 mL 0.6485 mL 0.8106 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Alpinoid D

New cytotoxic diarylheptanoids from the rhizomes of Alpinia officinarum.[Pubmed:18484537]

Planta Med. 2008 Mar;74(4):427-31.

Bioassay-guided fractionation of the cytotoxic MeOH extract from the rhizomes of Alpinia officinarum Hance led to the isolation of two new diarylheptanoids named Alpinoid D (1) and E (2), together with fifteen known diarylheptanoids (3 - 17). The structures of compounds 1 and 2 were elucidated on the basis of spectroscopic data and chemical evidence. The cytotoxic activity of the isolated diarylheptanoids was evaluated against the IMR-32 human neuroblastoma cell line. Among the tested compounds, 11, 12 and 14 exhibited the most potent activities with IC (50) values of 0.83, 0.23 and 0.11 microM, respectively.

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