Peramivir TrihydrateCAS# 1041434-82-5 |
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Quality Control & MSDS
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| Cas No. | 1041434-82-5 | SDF | Download SDF |
| PubChem ID | 11954371 | Appearance | Powder |
| Formula | C15H34N4O7 | M.Wt | 382.45 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | RWJ 270201 trihydrate; BCX 1812 trihydrate | ||
| Solubility | H2O : 6.6 mg/mL (17.26 mM; Need ultrasonic) | ||
| Chemical Name | (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid;trihydrate | ||
| SMILES | CCC(CC)C(C1C(CC(C1O)C(=O)O)N=C(N)N)NC(=O)C.O.O.O | ||
| Standard InChIKey | RFUCJKFZFXNIGB-ZBBHRWOZSA-N | ||
| Standard InChI | InChI=1S/C15H28N4O4.3H2O/c1-4-8(5-2)12(18-7(3)20)11-10(19-15(16)17)6-9(13(11)21)14(22)23;;;/h8-13,21H,4-6H2,1-3H3,(H,18,20)(H,22,23)(H4,16,17,19);3*1H2/t9-,10+,11+,12-,13+;;;/m0.../s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
IC50 Value: 0.09 nM
Target: Neuraminidase
Peramivir is an experimental antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. From Wikipedia References: | |||||
Peramivir Trihydrate Dilution Calculator
Peramivir Trihydrate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6147 mL | 13.0736 mL | 26.1472 mL | 52.2944 mL | 65.368 mL |
| 5 mM | 0.5229 mL | 2.6147 mL | 5.2294 mL | 10.4589 mL | 13.0736 mL |
| 10 mM | 0.2615 mL | 1.3074 mL | 2.6147 mL | 5.2294 mL | 6.5368 mL |
| 50 mM | 0.0523 mL | 0.2615 mL | 0.5229 mL | 1.0459 mL | 1.3074 mL |
| 100 mM | 0.0261 mL | 0.1307 mL | 0.2615 mL | 0.5229 mL | 0.6537 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
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Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.
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