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Altechromone A

CAS# 38412-47-4

Altechromone A

Catalog No. BCN7422----Order now to get a substantial discount!

Product Name & Size Price Stock
Altechromone A: 5mg $615 In Stock
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Quality Control of Altechromone A

Number of papers citing our products

Chemical structure

Altechromone A

3D structure

Chemical Properties of Altechromone A

Cas No. 38412-47-4 SDF Download SDF
PubChem ID 5316891 Appearance Powder
Formula C11H10O3 M.Wt 190.19
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 7-hydroxy-2,5-dimethylchromen-4-one
SMILES CC1=CC(=CC2=C1C(=O)C=C(O2)C)O
Standard InChIKey CRNGFKXWIYTEPH-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H10O3/c1-6-3-8(12)5-10-11(6)9(13)4-7(2)14-10/h3-5,12H,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Altechromone A

The metabolites of Alternaria brassicicola ML-P08.

Biological Activity of Altechromone A

Description1. Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
TargetsAntifection

Altechromone A Dilution Calculator

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Altechromone A Molarity Calculator

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Preparing Stock Solutions of Altechromone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2579 mL 26.2895 mL 52.579 mL 105.158 mL 131.4475 mL
5 mM 1.0516 mL 5.2579 mL 10.5158 mL 21.0316 mL 26.2895 mL
10 mM 0.5258 mL 2.6289 mL 5.2579 mL 10.5158 mL 13.1447 mL
50 mM 0.1052 mL 0.5258 mL 1.0516 mL 2.1032 mL 2.6289 mL
100 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.0516 mL 1.3145 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Altechromone A

Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB-18, an endophyte of Artemisia annua.[Pubmed:17253861]

J Nat Prod. 2007 Jan;70(1):114-7.

Two new benzo[j]fluoranthene-based secondary metabolites named daldinone C (1) and daldinone D (2), along with two known metabolites, Altechromone A and (4S)-5,8-dihydroxy-4-methoxy-alpha-tetralone, were isolated from the CHCl3/MeOH (1:1) extract of a solid culture of the endophyte Hypoxylon truncatum IFB-18 harbored inside the symptomless stem tissue of Artemisia annua. The structures of the new compounds were elucidated by MS and 1D and 2D NMR spectra and by X-ray diffraction analysis. Their absolute configurations were determined unambiguously by a combination of their CD data and the established exciton chirality rule. Compounds 1 and 2 were substantially cytotoxic against SW1116 cells, with IC50 values of 49.5 and 41.0 microM, respectively, comparable to that (37.0 microM) of 5-fluorouracil. The biosynthetic pathway for 1 and 2 was postulated with the natural occurrence of benzo[j]fluoranthene analogues discussed in brief.

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