Altechromone ACAS# 38412-47-4 |
Quality Control & MSDS
3D structure
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| Cas No. | 38412-47-4 | SDF | Download SDF |
| PubChem ID | 5316891 | Appearance | Powder |
| Formula | C11H10O3 | M.Wt | 190.19 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 7-hydroxy-2,5-dimethylchromen-4-one | ||
| SMILES | CC1=CC(=CC2=C1C(=O)C=C(O2)C)O | ||
| Standard InChIKey | CRNGFKXWIYTEPH-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C11H10O3/c1-6-3-8(12)5-10-11(6)9(13)4-7(2)14-10/h3-5,12H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The metabolites of Alternaria brassicicola ML-P08.
| Description | 1. Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. |
| Targets | Antifection |
Altechromone A Dilution Calculator
Altechromone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.2579 mL | 26.2895 mL | 52.579 mL | 105.158 mL | 131.4475 mL |
| 5 mM | 1.0516 mL | 5.2579 mL | 10.5158 mL | 21.0316 mL | 26.2895 mL |
| 10 mM | 0.5258 mL | 2.6289 mL | 5.2579 mL | 10.5158 mL | 13.1447 mL |
| 50 mM | 0.1052 mL | 0.5258 mL | 1.0516 mL | 2.1032 mL | 2.6289 mL |
| 100 mM | 0.0526 mL | 0.2629 mL | 0.5258 mL | 1.0516 mL | 1.3145 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon truncatum IFB-18, an endophyte of Artemisia annua.[Pubmed:17253861]
J Nat Prod. 2007 Jan;70(1):114-7.
Two new benzo[j]fluoranthene-based secondary metabolites named daldinone C (1) and daldinone D (2), along with two known metabolites, Altechromone A and (4S)-5,8-dihydroxy-4-methoxy-alpha-tetralone, were isolated from the CHCl3/MeOH (1:1) extract of a solid culture of the endophyte Hypoxylon truncatum IFB-18 harbored inside the symptomless stem tissue of Artemisia annua. The structures of the new compounds were elucidated by MS and 1D and 2D NMR spectra and by X-ray diffraction analysis. Their absolute configurations were determined unambiguously by a combination of their CD data and the established exciton chirality rule. Compounds 1 and 2 were substantially cytotoxic against SW1116 cells, with IC50 values of 49.5 and 41.0 microM, respectively, comparable to that (37.0 microM) of 5-fluorouracil. The biosynthetic pathway for 1 and 2 was postulated with the natural occurrence of benzo[j]fluoranthene analogues discussed in brief.
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