Arjunic acidCAS# 31298-06-3 |
Quality Control & MSDS
3D structure
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| Cas No. | 31298-06-3 | SDF | Download SDF |
| PubChem ID | 15385516 | Appearance | White powder |
| Formula | C30H48O5 | M.Wt | 488.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Synonyms | Arjuntriterpenic acid; 2α,3β,19α-Trihydroxyolean 12-ene 28-oic acid | ||
| Solubility | Soluble in methanol; insoluble in water | ||
| Chemical Name | (1S,4aR,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | ||
| SMILES | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1O)C)C(=O)O)C | ||
| Standard InChIKey | XJMYUPJDAFKICJ-YZTGESMESA-N | ||
| Standard InChI | InChI=1S/C30H48O5/c1-25(2)12-14-30(24(34)35)15-13-28(6)17(21(30)23(25)33)8-9-20-27(5)16-18(31)22(32)26(3,4)19(27)10-11-29(20,28)7/h8,18-23,31-33H,9-16H2,1-7H3,(H,34,35)/t18-,19+,20-,21-,22+,23+,27+,28-,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. |
| Targets | Antifection | COX |
| In vitro | Arjunic acid, a strong free radical scavenger from Terminalia arjuna.[Pubmed: 18306462]Am J Chin Med. 2008;36(1):197-207.This study was designed to investigate the antioxidant and free radical scavenging capacities of Arjunic acid, an aglycone obtained from the fruit of medicine Terminalia Fruit. Isolation and biological activities of termilignan B and arjunic acid from Terminalia sericea roots.[Pubmed: 18484533]Planta Med. 2008 Mar;74(4):411-3.Bioassay-guided fractionation of ethyl acetate root extracts of Terminalia sericea yielded a new compound, termilignan B, and the known Arjunic acid. |
Arjunic acid Dilution Calculator
Arjunic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0462 mL | 10.2312 mL | 20.4625 mL | 40.9249 mL | 51.1561 mL |
| 5 mM | 0.4092 mL | 2.0462 mL | 4.0925 mL | 8.185 mL | 10.2312 mL |
| 10 mM | 0.2046 mL | 1.0231 mL | 2.0462 mL | 4.0925 mL | 5.1156 mL |
| 50 mM | 0.0409 mL | 0.2046 mL | 0.4092 mL | 0.8185 mL | 1.0231 mL |
| 100 mM | 0.0205 mL | 0.1023 mL | 0.2046 mL | 0.4092 mL | 0.5116 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Isolation and biological activities of termilignan B and arjunic acid from Terminalia sericea roots.[Pubmed:18484533]
Planta Med. 2008 Mar;74(4):411-3.
Bioassay-guided fractionation of ethyl acetate root extracts of Terminalia sericea yielded a new compound, termilignan B, and the known Arjunic acid. Both compounds showed activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. The lowest MIC value (1.9 microg/mL) was observed with termilignan B against Bacillus subtilis. Neither of the compounds showed significant activity against Mycobacterium aurum A+. In the cyclooxygenase assays, the compounds showed weak inhibitory activity with IC (50) values of 78 microM (COX-1) and 156 microM (COX-2) (termilignan B) and 36 microM (COX-1) and 253 microM (COX-2) (Arjunic acid). No potential mutagenic effects were observed with the two compounds in the Salmonella microsome assay (TA 98).
Arjunic acid, a strong free radical scavenger from Terminalia arjuna.[Pubmed:18306462]
Am J Chin Med. 2008;36(1):197-207.
This study was designed to investigate the antioxidant and free radical scavenging capacities of Arjunic acid, an aglycone obtained from the fruit of medicine Terminalia Fruit. Liver microsomes, mitochondria, and red blood cells (RBCs) were prepared from Wistar rats. The antioxidant capacity was determined by the inhibitory effect on lipid peroxidation, hydrogen peroxide induced RBCs hemolysis, and RBCs autoxidative hemolysis. The free radical scavenging activity was tested by DPPH method and 2',7'-dichlorodihydrofluoresc in diacetate (DCFH(2)-DA) assay. Ascorbic acid was chosen as the positive controls. Results showed that Arjunic acid was a strong antioxidant and a free radical scavenger, more potent than ascorbic acid, in microsomes lipid peroxidation, DPPH, hydrogen peroxide induced RBCs hemolysis, and (DCFH(2)-DA) assay (p < 0.05). However, no significant difference was observed in the RBCs autoxidative hemolysis assay (p > 0.05).
