Camelliaside ACAS# 135095-52-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 135095-52-2 | SDF | Download SDF |
| PubChem ID | 5748475 | Appearance | Brown powder |
| Formula | C33H40O20 | M.Wt | 756.66 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Synonyms | Kaempferol 3-(2G-galactosylrutinoside) | ||
| Solubility | Soluble in methan | ||
| Chemical Name | 5,7-dihydroxy-3-[(2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2-(4-hydroxyphenyl)chromen-4-one | ||
| SMILES | CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)O)O)OC4=C(OC5=CC(=CC(=C5C4=O)O)O)C6=CC=C(C=C6)O)CO)O)O)O)O | ||
| Standard InChIKey | WSDPAECYOJCNFT-XAGFQBSHSA-N | ||
| Standard InChI | InChI=1S/C33H40O20/c1-10-19(39)23(43)25(45)31(47-10)51-28-21(41)17(9-35)50-33(30(28)53-32-26(46)24(44)20(40)16(8-34)49-32)52-29-22(42)18-14(38)6-13(37)7-15(18)48-27(29)11-2-4-12(36)5-3-11/h2-7,10,16-17,19-21,23-26,28,30-41,43-46H,8-9H2,1H3/t10-,16+,17+,19-,20-,21+,23+,24-,25+,26+,28-,30+,31-,32-,33+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Targets | NO | PGE | IL Receptor |
Camelliaside A Dilution Calculator
Camelliaside A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.3216 mL | 6.608 mL | 13.216 mL | 26.432 mL | 33.0399 mL |
| 5 mM | 0.2643 mL | 1.3216 mL | 2.6432 mL | 5.2864 mL | 6.608 mL |
| 10 mM | 0.1322 mL | 0.6608 mL | 1.3216 mL | 2.6432 mL | 3.304 mL |
| 50 mM | 0.0264 mL | 0.1322 mL | 0.2643 mL | 0.5286 mL | 0.6608 mL |
| 100 mM | 0.0132 mL | 0.0661 mL | 0.1322 mL | 0.2643 mL | 0.3304 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Novel synthesis of leucoside by enzymatic hydrolysis of tea seed extract.[Pubmed:22777867]
J Sci Food Agric. 2013 Jan;93(2):362-7.
BACKGROUND: The application of tea seed extract (TSE) has been widely investigated owing to its biological activities. In this paper, two flavonol triglycosides found in TSE, Camelliaside A (CamA) and camelliaside B (CamB), were subjected to hydrolysis in the presence of three commercial enzyme complexes of the Pectinex(R) series, 5XL, XXL and Ultra SP-L (Ultra). RESULTS: XXL and 5XL induced stepwise deglycosylation of CamA and CamB to yield kaempferol diglycoside (nicotiflorin), kaempferol monoglycoside (astragalin) and kaempferol, while Ultra produced an additional new compound (1) that had not been observed in earlier studies. Upon hydrolysis of isolated CamA and CamB, compound (1) was obtained only from CamB. Both the molecular ion peak in liquid chromatography/mass spectrometry and the (1)H and (1)(3)C nuclear magnetic resonance spectra of (1) isolated by Ultra-induced hydrolysis of TSE indicated that (1) was kaempferol 3-O-beta-xylopyranosyl (1 --> 2)-beta-glucopyranoside (leucoside), formed by selective hydrolysis of the rhamnosyl moiety of CamB. CONCLUSION: Pure leucoside can be prepared by enzymatic partial hydrolysis of TSE. This is the first study to address the synthesis of pure leucoside from a natural source.
Isolation and anti-inflammatory effect of astragalin synthesized by enzymatic hydrolysis of tea seed extract.[Pubmed:21567414]
J Sci Food Agric. 2011 Oct;91(13):2315-21.
BACKGROUND: The application of tea seed extract (TSE) has been widely investigated because of its biological activities. In this paper, two flavonol triglycosides in TSE-Camelliaside A (CamA) and camelliaside B (CamB)-were subjected to hydrolysis in the presence of two commercial enzyme complexes (Pectinex series): Smash and Mash. RESULTS: Smash hydrolyzed only the xylosyl moiety of CamB, and the main product was kaempferol diglycoside (nicotiflorin, NF). On the other hand, Mash induced the hydrolysis of both CamA and CamB, and kaempferol monoglycoside (astragalin, AS) was found to be a main product. Pure AS with > 96% purity was prepared by enzymatic hydrolysis of TSE using Mash, and the chemical structure of AS was confirmed by (1)H- and (13)C-nuclear magnetic resonance analyses. The prepared pure AS showed anti-inflammatory activities by significantly inhibiting cellular nitrite oxide (IC(50) = 363 microg mL(-1)), prostaglandin E(2) (IC(50) = 134 microg mL(-1)) and interleukin-6 production (IC(50) = 289 microg mL(-1)) by lipopolysaccharide -stimulated RAW 264.7 cells. CONCLUSION: It was concluded that pure AS can be prepared by enzymatic partial hydrolysis of TSE and employed as an anti-inflammatory material. This is the first study to address the preparation of pure AS from natural sources.
