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Caulophylline B

CAS# 1359978-55-4

Caulophylline B

Catalog No. BCN7499----Order now to get a substantial discount!

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Caulophylline B: 5mg $886 In Stock
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Quality Control of Caulophylline B

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Chemical structure

Caulophylline B

3D structure

Chemical Properties of Caulophylline B

Cas No. 1359978-55-4 SDF Download SDF
PubChem ID 134714941 Appearance Powder
Formula C19H21NO5 M.Wt 343.37
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-[2-(dimethylamino)ethyl]-4,5-dihydroxy-3,6-dimethoxyfluoren-9-one
SMILES CN(C)CCC1=CC(=C(C2=C1C(=O)C3=C2C(=C(C=C3)OC)O)O)OC
Standard InChIKey NAQHNUUPLJAHRT-UHFFFAOYSA-N
Standard InChI InChI=1S/C19H21NO5/c1-20(2)8-7-10-9-13(25-4)19(23)16-14(10)17(21)11-5-6-12(24-3)18(22)15(11)16/h5-6,9,22-23H,7-8H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Caulophylline B

The roots of Caulophyllum robustum Maxim.

Biological Activity of Caulophylline B

DescriptionCaulophylline B is a natural product from Caulophyllum robustum Maxim.

Protocol of Caulophylline B

Structure Identification
Fitoterapia. 2011 Sep;82(6):793-7.

Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim.[Pubmed: 21596111]


METHODS AND RESULTS:
Four new fluorenone alkaloids, caulophylline A, Caulophylline B, caulophylline C,caulophylline D (1-4), and one new dihydroazafluoranthene alkaloid, caulophylline E (5) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were elucidated by spectroscopic analysis.
CONCLUSIONS:
Among the isolated alkaloids, Caulophylline E showed good scavenging effects against DPPH radical with IC(50) of 39 μM.

Caulophylline B Dilution Calculator

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Caulophylline B Molarity Calculator

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Preparing Stock Solutions of Caulophylline B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9123 mL 14.5616 mL 29.1231 mL 58.2462 mL 72.8078 mL
5 mM 0.5825 mL 2.9123 mL 5.8246 mL 11.6492 mL 14.5616 mL
10 mM 0.2912 mL 1.4562 mL 2.9123 mL 5.8246 mL 7.2808 mL
50 mM 0.0582 mL 0.2912 mL 0.5825 mL 1.1649 mL 1.4562 mL
100 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.5825 mL 0.7281 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Caulophylline B

Four new fluorenone alkaloids and one new dihydroazafluoranthene alkaloid from Caulophyllum robustum Maxim.[Pubmed:21596111]

Fitoterapia. 2011 Sep;82(6):793-7.

Four new fluorenone alkaloids, caulophylline A-D (1-4), and one new dihydroazafluoranthene alkaloid, caulophylline E (5) were isolated from the roots of Caulophyllum robustum Maxim. Their structures were elucidated by spectroscopic analysis. Among the isolated alkaloids, Caulophylline E showed good scavenging effects against DPPH radical with IC(50) of 39 muM.

Description

Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical.

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