CimigenosideCAS# 27994-11-2 |
- Cimiracemoside C
Catalog No.:BCN5128
CAS No.:256925-92-5
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 27994-11-2 | SDF | Download SDF |
| PubChem ID | 16088242 | Appearance | White powder |
| Formula | C35H56O9 | M.Wt | 620.8 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Synonyms | Cimicifugol xyloside; Cimigenoside; Cimigoside | ||
| Solubility | Soluble in methanol; sparingly soluble in water | ||
| Chemical Name | (2S,3R,4S,5R)-2-[[(1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-hydroxy-22-(2-hydroxypropan-2-yl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracosan-9-yl]oxy]oxane-3,4,5-triol | ||
| SMILES | CC1CC2C(OC3(C1C4(CCC56CC57CCC(C(C7CCC6C4(C3O)C)(C)C)OC8C(C(C(CO8)O)O)O)C)O2)C(C)(C)O | ||
| Standard InChIKey | BTPYUWOBZFGKAI-XYGBCAHESA-N | ||
| Standard InChI | InChI=1S/C35H56O9/c1-17-14-19-26(30(4,5)40)44-35(43-19)25(17)31(6)12-13-34-16-33(34)11-10-22(42-27-24(38)23(37)18(36)15-41-27)29(2,3)20(33)8-9-21(34)32(31,7)28(35)39/h17-28,36-40H,8-16H2,1-7H3/t17-,18-,19-,20+,21+,22+,23+,24-,25-,26+,27+,28-,31-,32-,33-,34+,35+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Cimigenoside Dilution Calculator
Cimigenoside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.6108 mL | 8.0541 mL | 16.1082 mL | 32.2165 mL | 40.2706 mL |
| 5 mM | 0.3222 mL | 1.6108 mL | 3.2216 mL | 6.4433 mL | 8.0541 mL |
| 10 mM | 0.1611 mL | 0.8054 mL | 1.6108 mL | 3.2216 mL | 4.0271 mL |
| 50 mM | 0.0322 mL | 0.1611 mL | 0.3222 mL | 0.6443 mL | 0.8054 mL |
| 100 mM | 0.0161 mL | 0.0805 mL | 0.1611 mL | 0.3222 mL | 0.4027 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- H-Cys(Trt)-OH
Catalog No.:BCC2911
CAS No.:2799-07-7
- Bellidifolin
Catalog No.:BCN7424
CAS No.:2798-25-6
- Gardenin B
Catalog No.:BCN3816
CAS No.:2798-20-1
- Isosteviol
Catalog No.:BCN2685
CAS No.:27975-19-5
- 1,6-Dibromopyrene
Catalog No.:BCC8428
CAS No.:27973-29-1
- 2-Amino-3-chloro-1,4-naphthoquinone
Catalog No.:BCC8525
CAS No.:2797-51-5
- 14-Deoxy-epsilon-caesalpin
Catalog No.:BCN7254
CAS No.:279683-46-4
- H-Glu(OBzl)-OBzl.TosOH
Catalog No.:BCC2928
CAS No.:2791-84-6
- H-Lys(Z)-OMe.HCl
Catalog No.:BCC2988
CAS No.:27894-50-4
- Bis(4-bromophenyl)acetylene
Catalog No.:BCC8882
CAS No.:2789-89-1
- GW4064
Catalog No.:BCC4500
CAS No.:278779-30-9
- Croceic acid
Catalog No.:BCN2372
CAS No.:27876-94-4
- 25-O-methylcimigenol-3-O-beta-D-xylopyranoside
Catalog No.:BCN1464
CAS No.:27994-13-4
- 2,6-Bis(2-benzimidazolyl)pyridine
Catalog No.:BCC8504
CAS No.:28020-73-7
- Piperazine Ferulate
Catalog No.:BCN3277
CAS No.:171876-65-6
- Rediocide A
Catalog No.:BCN5175
CAS No.:280565-85-7
- VUF 5574
Catalog No.:BCC7030
CAS No.:280570-45-8
- SB 216763
Catalog No.:BCC3650
CAS No.:280744-09-4
- A 286982
Catalog No.:BCC3946
CAS No.:280749-17-9
- (+)-Ulopterol
Catalog No.:BCN1228
CAS No.:28095-18-3
- Chaetocin
Catalog No.:BCC2429
CAS No.:28097-03-2
- Adamantane
Catalog No.:BCN8481
CAS No.:281-23-2
- Pluviatolide
Catalog No.:BCN3041
CAS No.:28115-68-6
- H-Pro-OtBu
Catalog No.:BCC3020
CAS No.:2812-46-6
In vivo effects of black cohosh and genistein on estrogenic activity and lipid peroxidation in Japanese Medaka (Oryzias latipes).[Pubmed:15277055]
J Herb Pharmacother. 2003;3(3):33-50.
This study was designed to assay the estrogenic activities and the antioxidant potential of ethanol extracts from the herbal dietary supplement black cohosh (Cimicifuga racemosa) relative to the natural phytoestrogen genistein. The in vivo mechanisms of action of these two natural products have not been completely elucidated, and Japanese medaka (Oryzias latipes) provides a useful organism for initial in vivo screening of natural products. While both genistein and estradiol altered ovarian and testicular steroid release and decreased circulating testosterone levels in males, neither black cohosh total extract (75-30,000 ng/fish), cimiracemoside A, 25-O-methyl-Cimigenoside, actein, nor 26-deoxy-actein caused any differences in estrogenic activity compared to control fish. To assess antioxidant potential, animals were treated with natural products then challenged with 2-acetylaminofluorene (2-AAF) to induce lipid peroxidation (LPO) in the liver. Neither the total ethanol extracts from black cohosh nor its individual components showed an inhibitory effect in 2-AAF induced LPO. However, genistein manifested potent antioxidative activity in the LPO assay, with similar potency to a high dose of a-tocopherol. In contrast to genistein, black cohosh did not exhibit traditional estrogenic effects nor significant in vivo anti-oxidant potential in this fish model system.
