Cornoside

CAS# 40661-45-8

Cornoside

Catalog No. BCN7575----Order now to get a substantial discount!

Product Name & Size Price Stock
Cornoside: 5mg $529 In Stock
Cornoside: 10mg Please Inquire In Stock
Cornoside: 20mg Please Inquire Please Inquire
Cornoside: 50mg Please Inquire Please Inquire
Cornoside: 100mg Please Inquire Please Inquire
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Cornoside: 500mg Please Inquire Please Inquire
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Quality Control of Cornoside

Number of papers citing our products

Chemical structure

Cornoside

3D structure

Chemical Properties of Cornoside

Cas No. 40661-45-8 SDF Download SDF
PubChem ID 11809239 Appearance Powder
Formula C14H20O8 M.Wt 316.30
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-hydroxy-4-[2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]cyclohexa-2,5-dien-1-one
SMILES C1=CC(C=CC1=O)(CCOC2C(C(C(C(O2)CO)O)O)O)O
Standard InChIKey VTVARPTUBCBNJX-UJPOAAIJSA-N
Standard InChI InChI=1S/C14H20O8/c15-7-9-10(17)11(18)12(19)13(22-9)21-6-5-14(20)3-1-8(16)2-4-14/h1-4,9-13,15,17-20H,5-7H2/t9-,10-,11+,12-,13-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cornoside

The leaves of Abeliophyllum distichum.

Biological Activity of Cornoside

Description1. Cornoside and Iridoids are chemosystematic markers.

Cornoside Dilution Calculator

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Cornoside Molarity Calculator

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Preparing Stock Solutions of Cornoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1616 mL 15.8078 mL 31.6156 mL 63.2311 mL 79.0389 mL
5 mM 0.6323 mL 3.1616 mL 6.3231 mL 12.6462 mL 15.8078 mL
10 mM 0.3162 mL 1.5808 mL 3.1616 mL 6.3231 mL 7.9039 mL
50 mM 0.0632 mL 0.3162 mL 0.6323 mL 1.2646 mL 1.5808 mL
100 mM 0.0316 mL 0.1581 mL 0.3162 mL 0.6323 mL 0.7904 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cornoside

Analysis of the inhibitory activity of Abeliophyllum distichum leaf constituents against aldose reductase by using high-speed counter current chromatography.[Pubmed:23645536]

Arch Pharm Res. 2013 Sep;36(9):1104-12.

We isolated five phenolic glycosides (acteoside, eutigoside B, isoacteoside, rutin and Cornoside) from Abeliophyllum distichum leaves by high-speed counter current chromatography (HSCCC) using a solvent system of ethyl acetate:n-butanol:water (8:0.7:5). We determined the purity of the 5 compounds by high-performance liquid chromatography, and confirmed their chemical structures by using nuclear magnetic resonance data. We examined the inhibitory effect of these compounds on rat lens aldose reductase. Among these compounds, acteoside (1) showed the most potent inhibitory effect, with an IC(5)(0) value of 1.39 muM. The inhibitory effect of 1 was 5.0 times greater than that of quercetin (7.05 muM), which was used as a positive control. These results suggest that acteoside may be a promising agent for the prevention or treatment of diabetic complications. Moreover, HSCCC is a promising method for the isolation and purification of biologically active compounds from natural products.

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