DMT-ClCAS# 40615-36-9 |
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Quality Control & MSDS
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| Cas No. | 40615-36-9 | SDF | Download SDF |
| PubChem ID | 96831 | Appearance | Powder |
| Formula | C21H19ClO2 | M.Wt | 338.8 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in water or 1% acetic acid | ||
| Chemical Name | 1-[chloro-(4-methoxyphenyl)-phenylmethyl]-4-methoxybenzene | ||
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)Cl | ||
| Standard InChIKey | JBWYRBLDOOOJEU-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
DMT-Cl Dilution Calculator
DMT-Cl Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9516 mL | 14.758 mL | 29.5159 mL | 59.0319 mL | 73.7898 mL |
| 5 mM | 0.5903 mL | 2.9516 mL | 5.9032 mL | 11.8064 mL | 14.758 mL |
| 10 mM | 0.2952 mL | 1.4758 mL | 2.9516 mL | 5.9032 mL | 7.379 mL |
| 50 mM | 0.059 mL | 0.2952 mL | 0.5903 mL | 1.1806 mL | 1.4758 mL |
| 100 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.5903 mL | 0.7379 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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DMT-Cl
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Unusual C7- versus Normal 5'-O-Dimethoxytritylation of 6-Arylpyrrolocytidine Analogs.[Pubmed:27529362]
J Org Chem. 2016 Sep 16;81(18):8415-25.
Fluorescent deoxynucleosides possessing the modified bases 6-(2-benzo[b]furyl)- and 6-(2-furyl)pyrrolocytosine (BFpC and FpC) have been synthesized along with the quencher nucleosides possessing 6-{4-[(4-dimethylamino)azo]phenyl}pyrrolocytosine (DABCYLpC) and 6-(p-nitrophenyl)pyrrolocytosine (p-NO2-PhpC) nucleobase analogs. Standard treatment of BFpC, FpC, DABCYLpC, and p-NO2-PhpC with dimethoxytrityl chloride (DMT-Cl) led to the unusual substitution on the C7 of the pyrrolocytosine skeleton. The desired 5'-O-DMT-protected nucleoside analogs were synthesized from suitably protected 5'-O-DMT cytidines. Subsequent phosphitylation smoothly afforded BFpC-, FpC-, DABCYLpC-, and p-NO2-PhpC-derived monomers suitable for standard oligonucleotide synthesis.
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