Besifloxacin HClCAS# 405165-61-9 |
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Quality Control & MSDS
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| Cas No. | 405165-61-9 | SDF | Download SDF |
| PubChem ID | 10224595 | Appearance | Powder |
| Formula | C19H22Cl2FN3O3 | M.Wt | 430.3 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | H2O : < 0.1 mg/mL (insoluble) | ||
| Chemical Name | 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid;hydrochloride | ||
| SMILES | C1CCN(CC(C1)N)C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4CC4)F.Cl | ||
| Standard InChIKey | PMQBICKXAAKXAY-HNCPQSOCSA-N | ||
| Standard InChI | InChI=1S/C19H21ClFN3O3.ClH/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23;/h7,9-11H,1-6,8,22H2,(H,26,27);1H/t10-;/m1./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.
IC50 Value:
Target: Antibacterial
Besifloxacin has been found to inhibit production of pro-inflammatory cytokines in vitro. Besifloxacin is a novel 8-chloro-fluoroquinolone agent with potent, bactericidal activity against prevalent and drug-resistant pathogens.besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is particularly notable against gram-positive and gram-negative isolates that are resistant to other fluoroquinolones and classes of antibacterial agents. References: | |||||
Besifloxacin HCl Dilution Calculator
Besifloxacin HCl Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.324 mL | 11.6198 mL | 23.2396 mL | 46.4792 mL | 58.099 mL |
| 5 mM | 0.4648 mL | 2.324 mL | 4.6479 mL | 9.2958 mL | 11.6198 mL |
| 10 mM | 0.2324 mL | 1.162 mL | 2.324 mL | 4.6479 mL | 5.8099 mL |
| 50 mM | 0.0465 mL | 0.2324 mL | 0.4648 mL | 0.9296 mL | 1.162 mL |
| 100 mM | 0.0232 mL | 0.1162 mL | 0.2324 mL | 0.4648 mL | 0.581 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.
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Besifloxacin hydrochloride is a fourth-generation fluoroquinolone antibiotic.
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