Coronarin BCAS# 119188-38-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 119188-38-4 | SDF | Download SDF |
PubChem ID | 72702906 | Appearance | Powder |
Formula | C20H30O4 | M.Wt | 334.5 |
Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 7-(5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl)-3-hydroxy-4,7-dihydro-3H-dioxepine-5-carbaldehyde | ||
SMILES | CC1(CCCC2(C1CCC(=C)C2C3C=C(CC(OO3)O)C=O)C)C | ||
Standard InChIKey | FTQNGEYQJGYGFY-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C20H30O4/c1-13-6-7-16-19(2,3)8-5-9-20(16,4)18(13)15-10-14(12-21)11-17(22)24-23-15/h10,12,15-18,22H,1,5-9,11H2,2-4H3 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. Coronarin B has cytotoxic activity. 2. Coronarin B has modest antiplasmodial activity. |
Targets | Antifection |
Coronarin B Dilution Calculator
Coronarin B Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.9895 mL | 14.9477 mL | 29.8954 mL | 59.7907 mL | 74.7384 mL |
5 mM | 0.5979 mL | 2.9895 mL | 5.9791 mL | 11.9581 mL | 14.9477 mL |
10 mM | 0.299 mL | 1.4948 mL | 2.9895 mL | 5.9791 mL | 7.4738 mL |
50 mM | 0.0598 mL | 0.299 mL | 0.5979 mL | 1.1958 mL | 1.4948 mL |
100 mM | 0.0299 mL | 0.1495 mL | 0.299 mL | 0.5979 mL | 0.7474 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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Antiplasmodial activity of labdanes from Aframomum latifolium and Aframomum sceptrum.[Pubmed:12143001]
Planta Med. 2002 Jul;68(7):642-4.
Bioguided fractionation of extracts of Aframomum latifolium and A. sceptrum (Zingiberaceae) resulted in isolation of (+)-( S)-nerolidol and seven labdanes, Coronarin B, galanal A and B, galanolactone, ( E)-8beta,17-epoxylabd-12-ene-15,16-dial, (+)-( E)-labda-8(17), 12-diene-15,16-dial and its diethyl acetal, the latter being presumably an isolation artefact. The labdanes show a modest in vitro activity against a chloroquine-sensitive Plasmodium falciparum strain.