Cot inhibitor-2COT/Tpl2 inhibitor CAS# 915363-56-3 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 915363-56-3 | SDF | Download SDF |
| PubChem ID | 44143370 | Appearance | Powder |
| Formula | C26H25Cl2FN8 | M.Wt | 539.45 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 100 mg/mL (185.38 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile | ||
| SMILES | CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC(=C4C(=C3)C(=C(C=N4)C#N)NC5=CC(=C(C=C5)F)Cl)Cl | ||
| Standard InChIKey | PHNZIIMWDVXPGG-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C26H25Cl2FN8/c1-2-36-7-5-20(6-8-36)37-15-19(34-35-37)14-31-18-9-21-25(33-17-3-4-24(29)22(27)10-17)16(12-30)13-32-26(21)23(28)11-18/h3-4,9-11,13,15,20,31H,2,5-8,14H2,1H3,(H,32,33) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Cot inhibitor-2 is a COT/Tpl2 inhibitor. References: | |||||
Cot inhibitor-2 Dilution Calculator
Cot inhibitor-2 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.8537 mL | 9.2687 mL | 18.5374 mL | 37.0748 mL | 46.3435 mL |
| 5 mM | 0.3707 mL | 1.8537 mL | 3.7075 mL | 7.415 mL | 9.2687 mL |
| 10 mM | 0.1854 mL | 0.9269 mL | 1.8537 mL | 3.7075 mL | 4.6343 mL |
| 50 mM | 0.0371 mL | 0.1854 mL | 0.3707 mL | 0.7415 mL | 0.9269 mL |
| 100 mM | 0.0185 mL | 0.0927 mL | 0.1854 mL | 0.3707 mL | 0.4634 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cot inhibitor-2 is a COT/Tpl2 inhibitor.
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Cot inhibitor-2 is a COT/Tpl2 inhibitor.
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