DL-alpha-TocopherylacetateCAS# 7695-91-2 |
- alpha-Tocopherol acetate
Catalog No.:BCN5803
CAS No.:58-95-7
Quality Control & MSDS
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| Cas No. | 7695-91-2 | SDF | Download SDF |
| PubChem ID | 86472 | Appearance | Powder |
| Formula | C31H52O3 | M.Wt | 472.74 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate | ||
| SMILES | CC1=C2C(=C(C(=C1C)OC(=O)C)C)CCC(O2)(C)CCCC(C)CCCC(C)CCCC(C)C | ||
| Standard InChIKey | ZAKOWWREFLAJOT-CEFNRUSXSA-N | ||
| Standard InChI | InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Dl-alpha-Tocopherylacetate shows anti-inflammatory and analgesic activity, it acts synergistically with aspirin towards reducing inflammation and pain as well as the former reduced the gastric ulcerogenic potential of the latter. 2. Dl-alpha-Tocopherylacetate induces hypocoagulability and platelet hypoaggregability in rats. 3. Dl-alpha-tocopheryl acetate is a dietary supplement. |
| Targets | Immunology & Inflammation related |
DL-alpha-Tocopherylacetate Dilution Calculator
DL-alpha-Tocopherylacetate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1153 mL | 10.5766 mL | 21.1533 mL | 42.3066 mL | 52.8832 mL |
| 5 mM | 0.4231 mL | 2.1153 mL | 4.2307 mL | 8.4613 mL | 10.5766 mL |
| 10 mM | 0.2115 mL | 1.0577 mL | 2.1153 mL | 4.2307 mL | 5.2883 mL |
| 50 mM | 0.0423 mL | 0.2115 mL | 0.4231 mL | 0.8461 mL | 1.0577 mL |
| 100 mM | 0.0212 mL | 0.1058 mL | 0.2115 mL | 0.4231 mL | 0.5288 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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dl-alpha-Tocopheryl acetate induces hypocoagulability and platelet hypoaggregability in rats.[Pubmed:3440712]
Int J Vitam Nutr Res. 1987;57(4):375-9.
Rats receiving daily IP injections of dl-alpha-tocopheryl acetate (50 mg/kg) for 4 days showed levels of plasma alpha-tocopherol slightly increased and normal platelet count but platelet aggregation (induced by ADP or adrenaline) was significantly decreased when compared with the control animals. In addition, both platelet-rich plasma and platelet-poor plasma-thromboelastograms from treated rats showed thromboplastine-formation times significantly higher than those from control animals. Serum biochemical parameters showed several minor modifications in treated rats with respect the control ones. It suggests that vitamin E could be considered as a possible useful tool for the therapy of several hyperaggregable or hypercoagulable states.
Incorporation of alpha-tocopherol and linoleic acid in fresh lambs by feeding chemically treated dietary supplements containing dl-alpha-tocopheryl acetate and sunflower oil.[Pubmed:16417322]
J Agric Food Chem. 2006 Jan 25;54(2):568-73.
The effects of feeding chemically treated dietary supplements (CTDS) containing sunflower oil and dl-alpha-tocopheryl acetate (TA) on alpha-tocopherol content and fatty acid profile in edible tissues of lambs were estimated. Compared with lambs fed control diet (CD), lambs fed CD plus 250 IU of either TA or CTDS increased serum alpha-tocopherol. The CTDS-fed lambs further increased serum alpha-tocopherol by 29% over those fed CD plus 250 IU of TA. Lambs supplemented with TA or CTDS increased alpha-tocopherol in muscle and adipose tissues as compared with lambs fed CD. The CTDS-fed lambs had higher levels of alpha-tocopherol in gluteus medius (7.55 vs 6.05 mug/g), psoas major (7.43 vs 6.02 mug/g), and subcutaneous fat (12.6 vs 9.98 mug/g) compared with the TA-fed lambs. Feeding lambs CTDS also substantially increased levels of linoleic acid in the adipose tissues while decreasing the content of palmitic and oleic acids.
