Cleomiscosin BCAS# 76985-93-8 |
Quality Control & MSDS
3D structure
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| Cas No. | 76985-93-8 | SDF | Download SDF |
| PubChem ID | 156875 | Appearance | Powder |
| Formula | C20H18O8 | M.Wt | 386.36 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydropyrano[3,2-h][1,4]benzodioxin-9-one | ||
| SMILES | COC1=C(C=CC(=C1)C2C(OC3=C(C=C4C=CC(=O)OC4=C3O2)OC)CO)O | ||
| Standard InChIKey | XGADTAYOFHOFIW-NVXWUHKLSA-N | ||
| Standard InChI | InChI=1S/C20H18O8/c1-24-13-7-10(3-5-12(13)22)17-15(9-21)26-19-14(25-2)8-11-4-6-16(23)27-18(11)20(19)28-17/h3-8,15,17,21-22H,9H2,1-2H3/t15-,17-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Paederia scandens (Lour.) Merr
| Description | 1. Cleomiscosins A, B and C exhibit liver-protective properties. 2. Cleomiscosin B shows the potent anti-HIV-1 activity in vitro and also has protective effects on MT4 cells infected by HIV-1(IIIB). |
| Targets | HIV |
Cleomiscosin B Dilution Calculator
Cleomiscosin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.5883 mL | 12.9413 mL | 25.8826 mL | 51.7652 mL | 64.7065 mL |
| 5 mM | 0.5177 mL | 2.5883 mL | 5.1765 mL | 10.353 mL | 12.9413 mL |
| 10 mM | 0.2588 mL | 1.2941 mL | 2.5883 mL | 5.1765 mL | 6.4706 mL |
| 50 mM | 0.0518 mL | 0.2588 mL | 0.5177 mL | 1.0353 mL | 1.2941 mL |
| 100 mM | 0.0259 mL | 0.1294 mL | 0.2588 mL | 0.5177 mL | 0.6471 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Identification and quantification of two antihepatotoxic coumarinolignoids cleomiscosin A and cleomiscosin B in the seeds of Cleome viscosa using liquid chromatography-tandem mass spectrometry.[Pubmed:18800331]
Biomed Chromatogr. 2009 Apr;23(4):340-56.
A sensitive liquid chromatography/electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) method was developed for the identification and quantification of two antihepatotoxic coumarinolignoids cleomiscosin A and Cleomiscosin B in different extracts of the seeds of Cleome viscosa. The separation of cleomiscosin A and Cleomiscosin B was achieved on an RP(18) column using a solvent system consisting of a mixture of acetonitrile-methanol (1:2, v/v) and acetonitrile-water-formic acid (5:95:0.3, v/v) as a mobile phase in a gradient elution mode. A multiple-reaction monitoring (MRM) method was developed for quantification of cleomiscosin A and Cleomiscosin B in the seed extracts of Cleome viscosa. On the basis of signal-to-noise ratio of 3, the limit of detection in MRM mode for cleomiscosin A and Cleomiscosin B were 1.0 and 4.0 ng/mL respectively. The method was validated in terms of linearity, accuracy and precision for 6 days. The method developed was found to be useful for identification and quantification of cleomiscosin A and Cleomiscosin B in the different extracts of the seeds of Cleome viscosa.
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