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Desacetylcinobufotalin

CAS# 4099-30-3

Desacetylcinobufotalin

Catalog No. BCC8166----Order now to get a substantial discount!

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Quality Control of Desacetylcinobufotalin

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Chemical structure

Desacetylcinobufotalin

3D structure

Chemical Properties of Desacetylcinobufotalin

Cas No. 4099-30-3 SDF Download SDF
PubChem ID 20047 Appearance Powder
Formula C24H32O6 M.Wt 416.5
Type of Compound Steroids Storage Desiccate at -20°C
Synonyms Deacetylcinobufotalin
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC12CCC(CC1(CCC3C2CCC4(C35C(O5)C(C4C6=COC(=O)C=C6)O)C)O)O
Standard InChIKey FRYICJTUIXEEGK-VGKSGQJVSA-N
Standard InChI InChI=1S/C24H32O6/c1-21-8-5-14(25)11-23(21,28)10-7-16-15(21)6-9-22(2)18(13-3-4-17(26)29-12-13)19(27)20-24(16,22)30-20/h3-4,12,14-16,18-20,25,27-28H,5-11H2,1-2H3/t14-,15?,16?,18-,19+,20+,21+,22+,23-,24+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Desacetylcinobufotalin

The glandular body of Bufo bufo gargarizans Cantor.

Biological Activity of Desacetylcinobufotalin

Description1. Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway. 2. Desacetylcinobufotalin shows potent cytotoxic activities against HL-60 cell lines.

Desacetylcinobufotalin Dilution Calculator

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Desacetylcinobufotalin Molarity Calculator

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Preparing Stock Solutions of Desacetylcinobufotalin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.401 mL 12.0048 mL 24.0096 mL 48.0192 mL 60.024 mL
5 mM 0.4802 mL 2.401 mL 4.8019 mL 9.6038 mL 12.0048 mL
10 mM 0.2401 mL 1.2005 mL 2.401 mL 4.8019 mL 6.0024 mL
50 mM 0.048 mL 0.2401 mL 0.4802 mL 0.9604 mL 1.2005 mL
100 mM 0.024 mL 0.12 mL 0.2401 mL 0.4802 mL 0.6002 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on Desacetylcinobufotalin

Desacetylcinobufotalin is a natural compound; apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 0.0279μmol/ml.

References:
[1]. The Effect and Mechanism of Apoptosis Induced by Desacetylcinobufotalin (DEBF) in Human Hepatocellular Carcinoma HepG2 Cells

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Description

Desacetylcinobufotalin is a natural compound; apoptosis inducer and shows the marked inhibition effect to HepG2 cells and the IC50 value is 0.0279μmol/ml.

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